Wu, Fan published the artcileNickel-Catalyzed C-O Cross-Coupling Reaction at Low Catalytic Loading with Weak Base Participation, Formula: C9H8N2O, the main research area is diaryl ether preparation nickel catalyst coupling base.
Herein, the authors report a nickel-catalyzed cross-coupling reaction for the synthesis of diaryl ethers. The desired products are achieved by coupling heterocyclic alcs. with aryl bromides bearing strong electron withdrawing nitro group under the catalyst system of NiCl2(PPh3)2 and weak base KHCO3. This mild reaction exhibits a broad functional group tolerance. 5-(3, 4-Dichlorophenyl)-1-(4-nitrophenyl)-1H-pyrazol-3-ol as an important intermediate is suitable for further structural modification of MALT1 inhibitor MI-2.
European Journal of Organic Chemistry published new progress about Aromatic ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 27412-71-1 belongs to class pyrazoles-derivatives, name is 5-Phenyl-1H-pyrazol-3(2H)-one, and the molecular formula is C9H8N2O, Formula: C9H8N2O.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics