Burja, Bojan published the artcileA simple approach to pyrazol-3-ones via diazenes, Quality Control of 27412-71-1, the main research area is arylpropenoic acid oxalyl chloride activation methyl carbazate amidation; hydrazide arylpropenoic acid preparation oxidation zirconium tetrachloride cyclization; nitrogen protected arylpyrazolone preparation deprotection; arylpyrazolone preparation.
An efficient entry into pyrazol-3-ones is described starting from propenoic acids that were first transformed into the corresponding hydrazides. Oxidation of the hydrazides gave the diazenes and the latter cyclized to pyrazol-3-ones on treatment with ZrCl4. The methoxycarbonyl protection of the N-1 of the pyrazolone derivatives was easily removed under mild reaction conditions.
Tetrahedron published new progress about Amidation. 27412-71-1 belongs to class pyrazoles-derivatives, name is 5-Phenyl-1H-pyrazol-3(2H)-one, and the molecular formula is C9H8N2O, Quality Control of 27412-71-1.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics