On October 22, 2020, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard; Musumeci, Lucia; Jacques, Nicolas; Goffin, Eric published a patent.Recommanded Product: 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine The title of the patent was New pyrimidine derivatives for prevention and treatment of gram-negative bacterial infection, contamination and fouling. And the patent contained the following:
New pyrimidine derivatives together with a membrane penetrating agent, optionally with a detectable isotope and pharmaceutical composition for use in treatment or prevention of Gram-neg. bacterial infection in a host mammal in need of such treatment or prevention and use as inhibitors of Gram-neg. biofilm formation on a surface of biomaterial or medical device, particularly of cardiovascular device such as prosthetic heart valve or pacemakers. New pyrimidine derivatives together with a membrane penetrating agent; for use as radiotracer in diagnosing or prognosing Gram-neg. bacterial infection in a host mammal. The experimental process involved the reaction of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(cas: 85426-79-5).Recommanded Product: 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine
The Article related to antibacterial pyrimidine derivative, Pharmacology: Effects Of Antimicrobials and Parasiticides and other aspects.Recommanded Product: 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics