On May 21, 2019, Sun, Liangpeng; Piao, Huri; Xu, Lili published a patent.Recommanded Product: 36640-53-6 The title of the patent was 1,3-Diarylpyrazole PTP1B inhibitor containing carboxyalkyl rhodamine structure and preparation and application thereof. And the patent contained the following:
The invention provides a compound of 1,3-diarylpyrazole PTP1B inhibitor containing carboxyalkyl rhodamine structure as shown in the formula or a pharmaceutically acceptable salt thereof as a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor. Studies show that the inhibitor can effectively inhibit the activity of PTP1B and can be used as an insulin sensitizer for preventing and/or treating diseases related to insulin resistance mediated by PTP1B, particularly type II diabetes and obesity. The invention also provides a preparation method of the inhibitor. The experimental process involved the reaction of 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde(cas: 36640-53-6).Recommanded Product: 36640-53-6
The Article related to diarylpyrazole carboxyalkyl rhodamine preparation ptp1b inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.Recommanded Product: 36640-53-6
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics