On September 30, 2014, Ashok, D.; Ganesh, Arram; Ravi, S.; Lakshmi, B. Vijaya published an article.Reference of 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde The title of the article was Solvent-free microwave assisted synthesis and antimicrobial activity of new 2-{4-[3-(1-phenyl-3-aryl-1H-pyrazol-4-yl)-acryloyl]-phenyl}-isoindole-1,3-diones. And the article contained the following:
A series of new 2-(4-(3-(1-phenyl-3-aryl-1H-pyrazol-4-yl)-acryloyl)-phenyl)-isoindole-1,3-diones I (Ar = C6H5, 4-MeC6H4, 4-MeOC6H4, 4-BrC6H4, 2-naphthyl, etc.) have been synthesized by Claisen-Schmidt condensation of 2-(4-acetylphenyl)-isoindole-1,3-dione with 1-phenyl-3-aryl-1H-pyrazole-4-carbaldehydes in the presence of basic alumina under solvent-free microwave irradiation and conventional heating methods. All the synthesized compounds were screened for their antimicrobial activity. The activity was determined using cup plate agar diffusion method by measuring the zone of inhibition in mm. From the screening studies it is evident that the synthesized compounds I (Ar = Ph, 4-MeC6H4, 2-naphthyl) showed good antibacterial activity and compounds I (Ar = 4-MeOC6H4, 2-naphthyl) showed good antifungal activity against all the tested organisms. The experimental process involved the reaction of 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde(cas: 36640-53-6).Reference of 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde
The Article related to pyrazolyl acryloyl phenylisoindoledione preparation green chem microwave irradiation, solvent free antibacterial antifungal, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.Reference of 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics