Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5

The Article related to pyrimidine preparation antibacterial agent, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Application of 85426-79-5

On August 22, 2019, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard published a patent.Application of 85426-79-5 The title of the patent was Preparation of pyrimidine derivatives for use as antibacterial agents. And the patent contained the following:

Title compounds I [each X independently = N, CH, C(alkyl), etc.; Y = O or S; R1 and R2 independently = (un)substituted alkyl, alkenyl, aryl, etc.; each R3 independently = H, halo, OH, NO2, etc.; with provisions], and their pharmaceutically acceptable salts, are prepared and disclosed as antibacterial agents. Thus, e.g., II was prepared by a multistep procedure (preparation given). Select I were evaluated for antibacterial effects on S. epidermidis (ATCC25904), e.g., II demonstrated a minimal inhibitory concentration of 20-25 μM. The experimental process involved the reaction of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(cas: 85426-79-5).Application of 85426-79-5

The Article related to pyrimidine preparation antibacterial agent, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Application of 85426-79-5

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics