On August 7, 2014, Okura, Hironari; Kitajima, Kazuki; Kawahara, Atsuko; Wakita, Takeo; Kawase, Ayumi; Nomura, Michikazu published a patent.Electric Literature of 1014631-89-0 The title of the patent was Preparation of heterocyclic compounds as pest control agents. And the patent contained the following:
Disclosed are compounds I [G1 = nitrogen, carbon atom or CH; R1 = H, halo, cyano, etc.; m = 1-3; n = 0 or 1; Hy = 5- or 6-membered aromatic ring represented by Q1 (*2 is connection position to G2); A1 = carbon or nitrogen atom; A2 = carbon or sulfur atom; A3 = carbon or nitrogen atom; A4 = carbon or nitrogen atom; with a proviso that A1 and A2 cannot be carbon atom simultaneously; p = 0-2; q = 0 or 1; R2 = H, halo, alkyl, etc.; G2 = Q2 (*1 is connection position to Hy); Q = oxygen atom or NR5; R5 = H, alkyl, cycloalkyl, etc.; R3 = H, alkyl, cycloalkyl, etc.; R4 = alkyl, cycloalkyl, alkenyl, etc.; or salts thereof]. For example, compound II was prepared via reaction of thionicotinamide with chloroacetylacetone, condensation reaction with NH2OH and carbamoylation with ethylisocyanate. The invention compounds, e.g., II, showed ≥70% pesticidal activities for Laodelphax striatellus and Myzus persicae. The experimental process involved the reaction of 1-(Pyridin-3-yl)-1H-pyrazole-4-carboxylic acid(cas: 1014631-89-0).Electric Literature of 1014631-89-0
The Article related to heterocycle preparation pest control agent, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Electric Literature of 1014631-89-0
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics