In 1967,Micheel, Fritz; Dammert, Walter published 《Condensation products from trimethyl fluorotrimesate and α-amino-β-hydroxy compounds》.Chemische Berichte published the findings.Related Products of 15366-34-4 The information in the text is summarized as follows:
N-[6-carboxy-2,4-bis(methoxycarbonyl)phenyl]-DL-serinolactone (I) was treated with CH2N2 to form a pyrazoline which was converted to the corresponding cyclopropane derivative by elimination of N. The structures of the pyrazoline and cyclopropane derivatives were confirmed by degradation and synthesis. Condensates of DL-threonine and β-phenyl-DL-serine with methyl fluorotrimesate formed ester lactones, which on treatment with CH2N2 formed Me N-[2,4,6-(trimethoxycarbonyl)phenyl]-α-aminocrotonate and Me N-[2,4,6 (trimethoxycarbonyl)phenyl]-α-aminocinnamate, resp. In the experimental materials used by the author, we found Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4Related Products of 15366-34-4)
Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. The application of pyrazole derivatives in the development of anticancer agents has been thoroughly investigated and verified. Moreover, the medicinal features of a number of natural products incorporating pyrazole moiety such as pyrazofurin, pyrazofurin B, pyrazole-3(5)-carboxylic acid and 4-methylpyrazole-3(5)-carboxylic acid have been reported.Related Products of 15366-34-4
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics