de Araujo, Marcos Lopes’s team published research in Catalysis Today in 2021 | CAS: 930-36-9

1-Methylpyrazole(cas: 930-36-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Reference of 1-Methylpyrazole

de Araujo, Marcos Lopes; Correia, Gilvan Aguiar; Carvalho, Wagner Alves; Shul’pina, Lidia Sergeevna; Kozlov, Yuriy Nikitovich; Shul’pin, Georgiy Borisovich; Mandelli, Dalmo published their research in Catalysis Today on December 1 ,2021. The article was titled 《The effect of additives (pyrazine, pyrazole and their derivatives) in the oxidation of 2-butanol with FeCl3-H2O2 in aqueous solutions》.Reference of 1-Methylpyrazole The article contains the following contents:

In the present paper we described the oxidation of 2-butanol as a representative of secondary aliphatic alcs. The oxidizing system FeCl3-H2O2 was used. A kinetic study of the oxidation reaction has been carried out. Different substituted pyrazines and pyrazoles, namely 2-pyrazinecarboxylic acid (PCA), 5-methyl-2-pyrazinecarboxylic acid (5MPCA), 2-methylpyrazine (2MPZINE), 3-(trifluoromethyl)pyrazole (3TFMPZOLE), 3-methylpyrazole (3MPZOLE) and 1-methylpyrazole (1MPZOLE) were added as cooperating ligands in aqueous solutions DFT based calculations were also used in order to evaluate the different results obtained. Addition of PCA, 5MPCA and 3TFMPZOLE led to a better reaction performance, while the other ligands led to lower accumulation of products than the reaction without additives. Performed DFT studies suggested that the metal-ligand π-backbonding might be responsible for the reaction activity increase, while ligands more strongly bonded to Fe make it more difficult the access to the metal, leading to lower yields. After reading the article, we found that the author used 1-Methylpyrazole(cas: 930-36-9Reference of 1-Methylpyrazole)

1-Methylpyrazole(cas: 930-36-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Reference of 1-Methylpyrazole

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics