In 2019,New Journal of Chemistry included an article by Kandel, Shambhu; Sathish, Veerasamy; Mathivathanan, Logesh; Morozov, Alexander N.; Mebel, Alexander M.; Raptis, Raphael G.. Application of 114474-26-9. The article was titled 《Aggregation induced emission enhancement (AIEE) of tripodal pyrazole derivatives for sensing of nitroaromatics and vapor phase detection of picric acid》. The information in the text is summarized as follows:
Five pyrazole-based tripodal ligands, compounds1-5 (I,II,III,IV,V), based on a 1,3,5-triethylbenzene scaffold, show aggregation-induced emission enhancement (AIEE) and their application as fluorescent probes for detection of nitroaroms. is investigated. All five compounds are weakly fluorescent in THF, but their fluorescence intensity increases with the addition of a poor solvent (water), causing nanoaggregation, as confirmed by the changes in the UV-vis and emission spectra, and light scattering techniques. The nanoaggregates exhibit time-dependent emission characteristics and can serve as sensors for the detection of nitroarom. compounds The selective detection of picric acid (PA) over other nitroarom. compounds by 1-3 (I-III) is attributed to the photoinduced electron transfer from the trispyrazole to the quencher, as confirmed by TD-DFT calculations Furthermore, compounds 1(I) and 2 (II) were tested for sensing of PA in the vapor and solid phases by means of changes in the emission spectra observable by the naked eye. The supramol. assemblies of 1(I) and 3(III) with PA were structurally characterized by X-ray crystallog. In addition to this study using 4-(4-Nitrophenyl)-1H-pyrazole, there are many other studies that have used 4-(4-Nitrophenyl)-1H-pyrazole(cas: 114474-26-9Application of 114474-26-9) was used in this study.
4-(4-Nitrophenyl)-1H-pyrazole(cas: 114474-26-9) belongs to pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, monoamine oxidase inhibitory, anti-inflammatory, antipyretic, neuroleptic, anticonvulsant, antiarrhythmic, sedative, muscle relaxant, antidiabetic and antibacterial activities. Application of 114474-26-9
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics