In 2020,Catalysis Science & Technology included an article by Zhang, Shaoke; Weniger, Florian; Kreyenschulte, Carsten Robert; Lund, Henrik; Bartling, Stephan; Neumann, Helfried; Ellinger, Stefan; Taeschler, Christoph; Beller, Matthias. COA of Formula: C4H6N2. The article was titled 《Towards a practical perfluoroalkylation of (hetero)arenes with perfluoroalkyl bromides using cobalt nanocatalysts》. The information in the text is summarized as follows:
A convenient methodol. for perfluoroalkylation including trifluoromethylation of (hetero)arenes with perfluoroalkyl bromides was developed. Key for the success is the use of a specific cobalt-based nanocatalyst, which can be recycled at least up to 4 times. The scope of this first cobalt-catalyzed perfluoroalkylation is presented. In addition to this study using 1-Methylpyrazole, there are many other studies that have used 1-Methylpyrazole(cas: 930-36-9COA of Formula: C4H6N2) was used in this study.
1-Methylpyrazole(cas: 930-36-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. COA of Formula: C4H6N2
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics