In 1996,Bergstrom, Donald E.; Zhang, Peiming; Johnson, W. Travis published 《Design and synthesis of heterocyclic carboxamides as natural nucleic acid base mimics》.Nucleosides & Nucleotides published the findings.Product Details of 15366-34-4 The information in the text is summarized as follows:
A series of heterocyclic carboxamides have been designed as mimics for the natural nucleic acid bases. The nucleosides 1-(2′-deoxy-β-D-ribofuranosyl)imidazole-4-carboxamide (I), 1-(2′-deoxy-β-D-ribofuranosyl)pyrazole-3-carboxamide (II), and 1-(2′-deoxy-β-D-ribofuranosyl)pyrrole-3-carboxamide (III) were synthesized and their structures confirmed by spectroscopic and anal. means. In the part of experimental materials, we found many familiar compounds, such as Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4Product Details of 15366-34-4)
Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. The application of pyrazole derivatives in the development of anticancer agents has been thoroughly investigated and verified. Moreover, the medicinal features of a number of natural products incorporating pyrazole moiety such as pyrazofurin, pyrazofurin B, pyrazole-3(5)-carboxylic acid and 4-methylpyrazole-3(5)-carboxylic acid have been reported.Product Details of 15366-34-4
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics