Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 73616-27-0, name is 5-Amino-1-(2-hydroxyethyl)pyrazole, A new synthetic method of this compound is introduced below., 73616-27-0
To a solution of 5-AMINO-1-(2- hydroxyethyl) pyrazole (6.35 g) in a mixed solvent of ethanol (25 ml) and concentrated hydrochloric acid (0.035 ml) was added dropwise isoamyl nitrite (7.03 g). The mixture was stirred at room temperature for 17 hours. The crystalline residue was collected by filtration and dried in vacuo to give 5-amino-l- (2-hydroxyethyl)-4- nitrosopyrazole (4.0 g) as a solid. 1H-NMR (DMSO-d6) 8 3.68 (2H, t, J=5.5Hz), 3.94 (2H, t, J=5.5Hz), 4.89 (1H, br), 8.06 (2H, br), 8.53 (1H, s)
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.