《Esters of phosphorus oxy-acids as alkylating agents. II. N-Alkylation of imidazole and related heterocyclic compounds with trialkyl phosphates》 was written by Yamauchi, Kiyoshi; Kinoshita, Masayoshi. Formula: C7H12N2 And the article was included in Journal of the Chemical Society in 1973. The article conveys some information:
Imidazole, benzimidazole, pyrazole, 1,2,4-triazole, and benzotriazole reacted with (RO)3PO (R = Me, Et, Bu) to give N-alkyl derivatives (41-90%). Predominant N-1 alkylation was observed in the triazoles. In the part of experimental materials, we found many familiar compounds, such as 1-Butyl-1H-pyrazole(cas: 52096-24-9Formula: C7H12N2)
1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Formula: C7H12N2
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics