Reference of Methyl 1H-pyrazole-3-carboxylateIn 1992 ,《Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides》 appeared in Journal of Medicinal Chemistry. The author of the article were Manfredini, Stefano; Bazzanini, Rita; Baraldi, Pier Giovanni; Guarneri, Mario; Simoni, Daniele; Marongiu, Maria E.; Pani, Alessandra; La Colla, Paolo; Tramontano, Enzo. The article conveys some information:
Several pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-oneribonucleosides, e.g. I (R = R1 = H; R = R1 = H, Me, R = Br, iodo, R1 = H) and II (R2 = Me, CMe3, CH2Ph), were prepared and tested for antiviral/antitumor activities. Appropriate heterocyclic bases were prepared by standard methodologies. All compounds were evaluated in vitro for cytostatic and antiviral activity. In the experiment, the researchers used many compounds, for example, Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4Reference of Methyl 1H-pyrazole-3-carboxylate)
Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Reference of Methyl 1H-pyrazole-3-carboxylate
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics