《Quaternization and dequaternization of pyrazoles in solvent-free conditions: conventional heating versus microwave irradiation》 was written by Diez-Barra, Enrique; De la Hoz, Antonio; Sanchez-Migallon, Ana; Elguero, Jose. Reference of 1-Butyl-1H-pyrazole And the article was included in Journal of Heterocyclic Chemistry on August 31 ,1999. The article conveys some information:
A study on the quaternization and dequaternization of pyrazoles by conventional heating and microwave irradiation in solvent-free conditions is reported. Microwave irradiation produces an acceleration in the quaternization rate and a rapid equilibration between quaternized and non-quaternized products. Dequaternization is also more rapid and a change in the selectivity is observed using sym. pyrazolium salts. The experimental process involved the reaction of 1-Butyl-1H-pyrazole(cas: 52096-24-9Reference of 1-Butyl-1H-pyrazole)
1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Reference of 1-Butyl-1H-pyrazole
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics