Phosphine-Catalyzed Dearomative [3 + 2] Cycloaddition of Benzoxazoles with a Cyclopropenone was written by Wang, Xingben;Yu, Congjun;Atodiresei, Iuliana L.;Patureau, Frederic W.. And the article was included in Organic Letters in 2022.COA of Formula: C8H7NO2 This article mentions the following:
The triphenylphosphine catalyzed dearomative [3+2] cycloaddition of benzoxazoles I (R = H, F, Ph, Me, etc.; R1 = H, Me, F, Cl, Br, Et; RR1 = -CH=CH-CH=CH-; R2 = H, Me, F, Cl) with 1,2-diphenylcyclopropenone II (Ar = Ph, 3-methylphenyl) were described. The reaction scope, mechanism and possible future applications of this rare organocatalyzed cycloaddition were discussed. In the experiment, the researchers used many compounds, for example, 5-Methoxybenzo[d]oxazole (cas: 132227-03-3COA of Formula: C8H7NO2).
5-Methoxybenzo[d]oxazole (cas: 132227-03-3) belongs to benzoxazole derivatives. Although benzoxazole itself is of little practical value, many derivatives of benzoxazoles are commercially important. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.COA of Formula: C8H7NO2
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem