Day: November 25, 2022

Lu, Youcai published the artcileExtraction and Separation of Rare Earths from Nitrate Medium by Mixtures of p-Phosphorylated Calixarene and 1-Phenyl-3-methyl-4-benzoyl-pyrazalone-5, Safety of 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is Chinese Journal of Chemistry (2014), 32(10), 1077-1082, database is CAplus.

The gadolinium extraction by the mixtures of p-phosphorylated calixarene and 1-phenyl-3-methyl-4-benzoyl- pyrazalone-5 from nitrate medium was studied, which indicated an obvious synergistic effect between these two extractants. The extractants exhibit no interaction with each other before the metal extraction Gadolinium(III) was extracted by the species of Ln(PMBP)₂L₂(NO₃) instead of Ln(PMBP)₃·(HPMBP) or Ln(NO₃)₃·2L which are extracted by HPMBP or L alone. Thermodn. functions (ΔG, ΔH, ΔS) were calculated The extraction of other rare earths was also investigated and compared. Possible single rare earth separation was discussed.

Chinese Journal of Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Safety of 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Kang, Quan-Peng published the artcileSymmetric containing-PMBP N₂O₂-donors nickel(II) complexes: Syntheses, structures, Hirshfeld analyses and fluorescent properties, Formula: C17H14N2O2, the publication is Polyhedron (2019), 38-50, database is CAplus.

One mononuclear Ni(II) complex [Ni(L¹)(MeOH)₂]·MeOH (1) and two novel trinuclear Ni(II) complexes [Ni₃(L²)₃(EtOH)₆] (2) and [Ni₃(L²)₃(H₂O)₆] (3) constructed from sym. N₂O₂-donors chelating ligands (H₂L¹ and H₂L²) were synthesized and characterized by elemental analyses, FT-IR, UV-Vis spectra and fluorescence spectra. The structures of all three complexes were confirmed by single crystal x-ray diffraction analyses. Complex 1 includes one Ni(II) atom, one completely deprotonated (L¹)^2- unit and two coordinated methanol mols., and forms an infinite 2D supramol. network via the intermol. hydrogen bonds. While complex 2 or 3 is trinuclear with three Ni(II) atoms, three completely deprotonated (L²)^2- units and six coordinated ethanol or H₂O mols. These self-assembling complexes form different dimensional supramol. structures through inter- and intramol. hydrogen bonds. Hirshfeld surface analyses for complexes 1, 2 and 3 were mapped with various functions and further quantification of intermol. interactions was made through the generation of 2D fingerprint plots. In addition, the fluorescence titration experiments were used to characterize fluorescence properties of complexes 1 and 2.

Polyhedron published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Formula: C17H14N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Yu, Lingbo published the artcileSynthesis of 1-alkyl-4-amino-5-pyrazolecarboxylate and ethyl 1-alkyl-5-amino-4-pyrazolecarboxylate, Product Details of C7H11N3O2, the publication is Zhongguo Haiyang Daxue Xuebao, Ziran Kexueban (2006), 36(3), 54-58, database is CAplus.

Synthetic routes to two kinds of substituted pyrazole derivatives were designed based on an anal. of their structural features. The methods for preparing such heterocyclic intermediates, including an N-alkylation reaction condition are researched. The structures of 1-cyclopentyl-4-nitro-5-propyl-1H-pyrazole-3-carboxylic acid Et ester and 1-cyclopentyl-4-nitro-3-propyl-1H-pyrazole-5-carboxylic acid Et ester were identified by HMBC and INEPT NMR techniques.

Zhongguo Haiyang Daxue Xuebao, Ziran Kexueban published new progress about 23286-70-6. 23286-70-6 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Amine,Ester, name is Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, and the molecular formula is C15H21BO3, Product Details of C7H11N3O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Xu, Sheng-jie published the artcileSynthesis and cytotoxicity of some pyrazolic compounds, Name: 4-(1H-Pyrazol-4-yl)pyridine, the publication is Guangzhou Huagong (2012), 40(24), 47-48, database is CAplus.

Seven pyrazole compounds were synthesized and characterized by ¹H NMR and MS, and the cytotoxicity of the compounds on Bel-7402, KB, HL-60, and BGC-823 was tested by MTT assay. The results showed that compound 4f exhibited higher cytotoxicity against Bel-7402 and BGC-823 cell lines.

Guangzhou Huagong published new progress about 19959-71-8. 19959-71-8 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Pyridine, name is 4-(1H-Pyrazol-4-yl)pyridine, and the molecular formula is C13H10O2, Name: 4-(1H-Pyrazol-4-yl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Xu, Shengjie published the artcileDesign, synthesis, and biologic evaluation of some novel N-arylpyrazole derivatives as cytotoxic agents, Application In Synthesis of 19959-71-8, the publication is Medicinal Chemistry Research (2013), 22(11), 5610-5616, database is CAplus.

A novel series of N-arylpyrazole derivatives I(R = 4-CF₃, 3,5-(CF₃)₂, 4-NO₂), II, III and IV(R = H, OC₈H₁₇) has been designed and synthesized via aromatic substitution reaction of N-nonsubstituted pyrazoles with 4-fluoronitrobenzene in the presence of base. The structures of these compounds were established on the basis of elemental (C, H, and N) and spectral anal. (¹H NMR, ¹³C NMR, HRMS, and FT-IR). All the compounds were tested for their cytotoxic activity in vitro against four human tumor cell lines: carcinoma (Bel-7402), nasopharyngeal carcinoma (KB), immature granulocyte leukemia (HL-60), and gastrocarcinoma (BGC-823) by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The results showed that most of the obtained compounds exhibited promising cytotoxicity against tested carcinoma cell lines with low IC₅₀ values. The bis-pyrazole derivative IV(R = OC₈H₁₇), bearing alkoxy group on the 5-position of Ph ring, was the most effective one. It is inhibition of cell growth of Bel-7402 cells was 1.5-fold higher than that found for cisplatin. And, also mono-pyrazole derivatives I(R = 4-CF₃, 3,5-(CF₃)₂) decorated with trifluoromethyl group on the Ph ring, displayed better cytotoxicity than that of cisplatin against Bel-7402 cell line.

Medicinal Chemistry Research published new progress about 19959-71-8. 19959-71-8 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Pyridine, name is 4-(1H-Pyrazol-4-yl)pyridine, and the molecular formula is C18H10F3NO3S2, Application In Synthesis of 19959-71-8.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics