Day: November 25, 2022

Wipf, Peter published the artcileMetathesis reactions of pyrazolotriazinones generate dynamic combinatorial libraries, Product Details of C7H10N2O2, the publication is Organic Letters (2005), 7(20), 4483-4486, database is CAplus and MEDLINE.

Reversible metathesis reactions of pyrazolotriazinones and aliphatic aldehydes or ketones proceed in aqueous, phosphate-buffered media at pH 4 and 40-60 °C to generate thermodynamically controlled mixtures of heterocycles.

Organic Letters published new progress about 890590-91-7. 890590-91-7 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Carboxylic acid, name is 3-Isopropyl-1H-pyrazole-5-carboxylic acid, and the molecular formula is C3H6O2, Product Details of C7H10N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil M. published the artcileDyeing performance of heterocyclic monoazo dyes based on 3-amino-1H-pyrazolon[3,4-b]quinoline derivatives on various fibers, Application of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Archives of Applied Science Research (2011), 3(4), 359-365, database is CAplus.

1H-Pyrazolo[3,4-b]quinolin-3-amine derivatives have been synthesized by the reaction between substituted Ph pyrazolones and 3-amino-1H-pyrazolon[3,4-b]quinoline. The novel compound structures have been established on the basis of their substituted Ph pyrazolones derivatives All the azo compounds were characterized by their percentage yield, m.p., elemental anal., UV visible spectra, IR spectra, NMR spectra and dyeing performance on nylon, wool, silk and polyester fibers. All the synthesized dyes gave moderate to excellent fastness properties on each fiber.

Archives of Applied Science Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Application of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil M. published the artcileSynthesis of heterocyclic monoazo dyes derived from 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine: their antimicrobial activity and their dyeing performance on various fibers, Application In Synthesis of 14580-22-4, the publication is Research on Chemical Intermediates (2012), 38(3-5), 885-901, database is CAplus.

Heterocyclic monoazobenzoquinoline-based azo dyes have been derived by diazotization of 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine with a variety of phenylpyrazolone-based coupling compounds The synthesized dyes were characterized by determination of their percentage yield, by elemental anal., and by UV-visible, IR, and ¹H NMR spectroscopy. Dyeing performance on silk, wool, nylon, and polyester fibers was assessed. The fastness properties of the dyes on each fiber were moderate to excellent. The antimicrobial activity of the dyes at different concentrations were also examined, by use of the Kirby-Bauer disk diffusion method.

Research on Chemical Intermediates published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Application In Synthesis of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil M. published the artcileAntituberculosis and antibacterial evaluations of some novel phenyl pyrazolone-substituted 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine derivatives, Product Details of C10H9ClN2O, the publication is Medicinal Chemistry Research (2012), 21(12), 4168-4176, database is CAplus.

Coupling of various phenylpyrazolone derivatives with diazonium salt of 1H-benzo[g]pyrazolo[3,4-b]quinolin-3-ylamine gave a series of heterocyclic azo compounds All the synthesized azo compounds have been characterized by their percentage yield, elemental, and spectral analyses. These new compounds were evaluated for their in vitro antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa. Furthermore, the synthesized compounds were tested for in vitro antituberculosis activity against Mycobacterium tuberculosis. Streptomycin, Isoniazid, Rifampicin, and Ethambutol were used as standards in this investigation.

Medicinal Chemistry Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Product Details of C10H9ClN2O.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil M. published the artcileColorimetric studies of heterocyclic monoazo dyes on various fibres, Recommanded Product: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Indian Journal of Fibre & Textile Research (2012), 37(4), 372-377, database is CAplus.

A series of heterocyclic monoazo quinazolinone based heterocyclic monoazo dyes derived by the diazotization of 3-(4-aminophenyl)-2-phenylquinazolin-4(3H)-one with various Ph pyrazolones based coupling components has been studied. These dyes give mostly yellow shades. All the heterocyclic monoazo dyes have been characterized by their % yield, UV-VIS spectroscopy, IR spectroscopy, ¹H NMR spectroscopy, and dyeing performance on silk, wool, nylon, and polyester fibers. The percentage dye bath exhaustion on different fibers is found to be reasonably good and acceptable. The dyed fibers show moderate to very good light fastness and good to excellent washing and rub fastness properties. Spectral properties and colorimetric data (L*, a*, b*, C*, H*, K/S) have also been investigated.

Indian Journal of Fibre & Textile Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Recommanded Product: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil published the artcileStudy on antibacterial activity for multidrug resistance stain by using phenyl pyrazolones substituted 3-amino 1H-pyrazolon (3,4-b) quinoline derivative in vitro condition, HPLC of Formula: 14580-22-4, the publication is International Journal of PharmTech Research (2011), 3(1), 540-548, database is CAplus.

3-Methyl-1-phenyl-4-[(E)-2-{1H-pyrazolo [3,4-b] quinolin-3-yl} diazen-1-yl]-4,5-dihydro-1H-pyrazol-5-one derivative have been synthesized by the reaction between substituted Ph pyrazolones and 3-amino-1 H-pyrazolo [3,4-b] quinoline. The novel compound structure has been established on the basis of their substituted Ph pyrazolones derivatives These compounds were tested for in vitro antifungal or antibacterial activity against Gram-Pos. and Gram-Neg. stain by standard method and synthesized compounds showed moderate to good antibacterial and antifungal activity with respect to standard drugs Ciprofloxacin and Flucanazole.

International Journal of PharmTech Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, HPLC of Formula: 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil published the artcileStudies on antimicrobial activity for multidrug resistance strain by using phenyl pyrazolones substituted 3-(4-aminophenyl)-2-phenylquinazolin-4(3H)-one derivatives in vitro condition and their dyeing performance, SDS of cas: 14580-22-4, the publication is Fibers and Polymers (2012), 13(2), 162-168, database is CAplus.

Heterocyclic monoazo quinazolinone based azo dyes derived by the diazotization of 3-(4-aminophenyl)-2-phenylquinazolin-4(3H)-one with various Ph pyrazolones based coupling components. All the heterocyclic azo dyes were characterized by their percentage yield, UV-VIS spectroscopy, elemental anal., IR spectroscopy, ¹H NMR spectroscopy, and dyeing performance on silk, wool, nylon, and polyester fibers. All the dyes gave moderate to excellent fastness properties on each fiber. The main focus was to synthesize heterocyclic monoazo dyes that give good dyeing property along with pharmacol. activity (anti bacterial and antifungal). Therefore, the synthesized compounds were examined for their antimicrobial activity at various concentrations using well-known Kirby-Bauer disk diffusion method.

Fibers and Polymers published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, SDS of cas: 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Chauhan, Pankaj published the artcileAsymmetric Synthesis of Amino-Bis-Pyrazolone Derivatives via an Organocatalytic Mannich Reaction, Category: pyrazoles-derivatives, the publication is Journal of Organic Chemistry (2017), 82(13), 7050-7058, database is CAplus and MEDLINE.

A new series of N-Boc ketimines derived from pyrazolin-5-ones have been used as electrophiles in asym. Mannich reactions with pyrazolones. The amino-bis-pyrazolone products are obtained in excellent yields and stereoselectivities by employing a very low loading of 1 mol % of a bifunctional squaramide organocatalyst. Depending on the substitution at position 4 of the pyrazolones, the new protocol allows for the generation of one or two tetrasubstituted stereocenters, including a one-pot version combing the Mannich reaction with a base-mediated halogenation.

Journal of Organic Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Category: pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Brzozowski, Zdzislaw published the artcileDerivatives of 1-pyrazole carboxylic acid. I. Synthesis of certain 1-pyrazolecarbonyl chlorides, Name: 1H-Pyrazole-1-carbonyl chloride, the publication is Acta Poloniae Pharmaceutica (1981), 38(4), 393-8, database is CAplus.

Fifteen acid chlorides I (R = H, Me, Et; R¹ = H, Me, Et, Pr, Bu, PhCH₂ Cl; R² = H and Me) were prepared in 87-98% yield from the corresponding 1H– pyrazoles and COCl₂ in PhMe. Three I were converted into the corresponding amides by reaction with NH₃(g) in Et₂O. The mass spectral fragmentation of 3-ethyl-4-methyl-1-pyrazole carboxamide is presented.

Acta Poloniae Pharmaceutica published new progress about 53355-55-8. 53355-55-8 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Chloride,acyl chloride,Amide, name is 1H-Pyrazole-1-carbonyl chloride, and the molecular formula is C4H3ClN2O, Name: 1H-Pyrazole-1-carbonyl chloride.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Brzozowski, Zdzislaw published the artcileDerivatives of pyrazole-1-carboxylic acid. II. Synthesis of certain 4-[2-(1-pyrazolecarboxamido)ethyl]benzenesulfonamides, Synthetic Route of 53355-55-8, the publication is Acta Poloniae Pharmaceutica (1981), 38(4), 399-405, database is CAplus.

Fifteen title compounds (I, R = H, Me, Et; R¹ = H, Me, Et, Pr, Bu, PhCH₂, Cl; R² = H, Me) were prepared in 55-91% yields from the corresponding 1-pyrazolecarbonyl chlorides and 4-H₂NSO₂C₆H₄(CH₂)₂NH₂ in Et₃N (or NaOH in aqueous Me₂CO). Some I were also obtained in the reaction of 4-H₂NSO₂C₆H₄(CH₂)₂NHCONHNH₂ (II) with BzOCH:CR¹COR in AcOH. I (R = Me, R¹ = R² = H) was addnl. prepared also from II and MeCOCH₂CH(OEt)₂. To prepare II, I (R = R² = Me, R¹ = H) was heated with N₂H₄ in EtOH.

Acta Poloniae Pharmaceutica published new progress about 53355-55-8. 53355-55-8 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Chloride,acyl chloride,Amide, name is 1H-Pyrazole-1-carbonyl chloride, and the molecular formula is C4H3ClN2O, Synthetic Route of 53355-55-8.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics