An update on the compound challenge: C5H8N2

Welcome to talk about 67-51-6, If you have any questions, you can contact Champaka, G; Senthilkumar, K; David, E; Shanmugan, S; Palanisami, N or send Email.. Category: pyrazoles-derivatives

Category: pyrazoles-derivatives. In 2021.0 J MOL STRUCT published article about BIOORGANOMETALLIC CHEMISTRY; CRYSTAL-STRUCTURE; METAL-COMPLEXES; AMINO-ACIDS; DERIVATIVES; PYRAZOLE in [Champaka, Gurudevaru; Senthilkumar, Kabali; David, Ezhumalai; Palanisami, Nallasamy] Vellore Inst Technol, Ctr Funct Mat, Dept Chem, Sch Adv Sci, Vellore 632014, Tamil Nadu, India; [Shanmugan, Swaminathan] SRM Inst Sci & Technol, Dept Chem, Fac Engn & Technol, Kancheepuram 603203, Tamil Nadu, India in 2021.0, Cited 40.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

Monomeric zinc ferrocene carboxylate [Zn(FcCOO)(3,5-dmp)(2)Cl] (1) has been synthesized from a reaction between the zinc chloride, sodium salt of ferrocene carboxylic acid (FcCOONa) and 3,5-dimethylpyrazole (3,5-dmp) at room temperature. Compound 1 was further characterized by elemental analysis, H-1 NMR, FT-IR, absorption, emission spectroscopic techniques, and molecular structure was confirmed by single-crystal X-ray diffraction studies. The molecular structure of compound 1 crystallized in triclinic system with P (1) over bar space group and the central Zn2+ ion is in a distorted tetrahedral geometry with -FeN2OCl coordination environment. Compound 1 was further stabilized with the aid of inter and intramolecular hydrogen bonding and pi-pi interaction between cyclopentadienyl ring of ferrocene and aromatic heterocyclic five membered 3,5-dimethylpyrazole. Compound 1 exhibits broad emission band, indicating ligandto-metal charger transfer (LMCT) or metal-to-ligand charger transfer (MLCT) nature. The electrochemical property of compound 1 revealed that one-electron anodic and cathodic peaks corresponding to the redox responsible of ferrocene/ferrocenium (FeII <-> Fe-III) moiety. Among the different strains of bacteria, the antibacterial activity of compound 1 showed comparatively a significant activity against gram negative bacterium Proteus vulgaris. (C) 2020 Elsevier B.V. All rights reserved.

Welcome to talk about 67-51-6, If you have any questions, you can contact Champaka, G; Senthilkumar, K; David, E; Shanmugan, S; Palanisami, N or send Email.. Category: pyrazoles-derivatives

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Downstream Synthetic Route Of 83-10-3

Category: pyrazoles-derivatives. About 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid, If you have any questions, you can contact Peters, GA; Wong, ML; Joseph, JW; Sanchez, LD or concate me.

Authors Peters, GA; Wong, ML; Joseph, JW; Sanchez, LD in JMIR PUBLICATIONS, INC published article about HEART-RATE-VARIABILITY; WORK-LIFE BALANCE; BURNOUT; SURGEONS; STRESS; SATISFACTION; TONE in [Peters, Gregory Andrew; Wong, Matthew L.; Joseph, Joshua W.; Sanchez, Leon D.] Beth Israel Deaconess Med Ctr, Dept Emergency Med, 1 Deaconess Rd, Boston, MA 02215 USA; [Peters, Gregory Andrew; Wong, Matthew L.; Joseph, Joshua W.; Sanchez, Leon D.] Harvard Med Sch, Boston, MA 02115 USA in 2019, Cited 40. Category: pyrazoles-derivatives. The Name is 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Through research, I have a further understanding and discovery of 83-10-3

Background: The high prevalence of physician burnout, particularly in emergency medicine, has garnered national attention in recent years. Objective means of measuring stress while at work can facilitate research into stress reduction interventions, and wearable photoplethysmography (PPG) technology has been proposed as a potential solution. However, the use of low-burden wearable biosensors to study training and clinical practice among emergency physicians (EP) remains untested. Objective: This pilot study aimed to (1) determine the feasibility of recording on-shift photoplethysmographic data from EP, (2) assess the quality of these data, and (3) calculate standard pulse rate variability (PRV) metrics from the acquired dataset and examine patterns in these variables over the course of an academic year. Methods: A total of 21 EP wore PPG biosensors on their wrists during clinical work in the emergency department during a 9-hour shift. Recordings were collected during the first quarter of the academic year, then again during the fourth quarter of the same year for comparison. The overall rate of usable data collection per time was computed. Standard pulse rate (PR) and PRV metrics from these two time points were calculated and entered into Student t tests. Results: More than 400 hours of data were entered into these analyses. Interpretable data were captured during 8.54% of the total recording time overall. In the fourth quarter of the academic year compared with the first quarter, there was no significant difference in median PR (75.8 vs 76.8; P=.57), mean R-R interval (0.81 vs 0.80; P=.32), SD of R-R interval (0.11 vs 0.11; P=.93), root mean square of successive difference of R-R interval (0.81 vs 0.80; P=.96), low-frequency power (3.5×103 vs 3.4×103; P=.79), high-frequency power (8.5×103 vs 8.3×103; P=.91), or low-frequency to high-frequency ratio (0.42 vs 0.41; P=.43), respectively. Power estimates for each of these tests exceeded .90. A secondary analysis of the resident-only subgroup similarly showed no significant differences over time, despite power estimates greater than .80. Conclusions: Although the use of PPG biosensors to record real-time physiological data from EP while providing clinical care seems operationally feasible, this study fails to support the notion that such an approach can efficiently provide reliable estimates of metrics of interest. No significant differences in PR or PRV metrics were found at the end of the year compared with the beginning. Although these methods may offer useful applications to other domains, it may currently have limited utility in the contexts of physician training and wellness.

Category: pyrazoles-derivatives. About 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid, If you have any questions, you can contact Peters, GA; Wong, ML; Joseph, JW; Sanchez, LD or concate me.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

New learning discoveries about C5H8N2

Product Details of 67-51-6. Welcome to talk about 67-51-6, If you have any questions, you can contact Cimino, S; Verze, P; Venturino, L; Alessio, P; Migliara, A; Imbimbo, C; Mirone, V; Russo, GI; Morgia, G or send Email.

Recently I am researching about RESISTANCE, Saw an article supported by the . Published in ELSEVIER in AMSTERDAM ,Authors: Cimino, S; Verze, P; Venturino, L; Alessio, P; Migliara, A; Imbimbo, C; Mirone, V; Russo, GI; Morgia, G. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole. Product Details of 67-51-6

Background: Transrectal ultrasound-guided prostate biopsy (TRBx) or transperineal Bx (TPBx) are considered alternative approaches for the diagnosis of prostate cancer (PCa). However, urinary tract infection (UTI) or other complications could be more frequent in the TRBx approach. Objective: To determine the complication rate following different antimicrobial prophylaxis (AMP; fosfomycin trometamol [FT] vs beta-lactame or fluorochinolones [FQ]) in patients undergoing TRBx or TPBx. Design, setting, and participants: The analyses were based on prospectivelycollected data of a cohort of patients who underwent TRBx or TPBx for elevated prostate-specific antigen (PSA; >= 4 ng/ml) or clinical suspicion of PCa, between September 2016 and March 2017. Patients received a single dose of 3 g oral FT (group A) or, alternatively, FQ or beta-lactame (group B). Intervention:TRBx versus TPBx. Outcome measurements and statistical analysis: Adjustment variables consisted of age, PSA, biopsy technique (TPBx vs TRBx), and antibiotic prophylaxis (FT vs beta-lactame or FQ) using 1:1 propensity-score matching. Overall, 526 patients were considered, of whom 258 received FT (group A) and the other 258 received beta-lactame or FQ (group B). Results and limitations: Overall complications occurred in 390 (75.58%) and major complications in 67/516 (12.98%). Lower prevalence of UTIs was detected in group A (34.1%) compared with that in group B (43.4%; p = 0.03), while similar rates of haematuria (54.7% vs 55.4%), haemospermia (39.5% vs 33.0%), and acute urinary retention (11.6% vs 9.3%) were detected in groups A and B. We found that group B (odds ratio [OR]: 1.54; p = 0.03), I grade haematuria (OR: 6.17; p < 0.01), and II grade haematuria (OR: 5.13; p < 0.01) were significantly associated with increased risk of UTIs. Conclusions: AMP with fluoroquinoles or beta-lactam antibiotics increased the rate of UTIs, when compared with FT, in patients undergoing TRBx or TPBx. The appearance of haematuria or haemospermia is associated with UTIs, suggesting the possibility of tailoring the strategy for prophylaxis in this category of patients. Patient summary: In this study, comparing complications after transrectal ultrasound-guided prostate biopsy versus transperineal biopsy, prophylaxis with fluoroquinoles or beta-lactam antibiotics increased the rate of urinary tract infections when compared with fosfomycin trometamol, regardless of the type of biopsy approach. (C) 2018 European Association of Urology. Published by Elsevier B.V. All rights reserved. Product Details of 67-51-6. Welcome to talk about 67-51-6, If you have any questions, you can contact Cimino, S; Verze, P; Venturino, L; Alessio, P; Migliara, A; Imbimbo, C; Mirone, V; Russo, GI; Morgia, G or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Now Is The Time For You To Know The Truth About 3-Methyl-1-p-tolyl-5-pyrazolone

Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.. Category: pyrazoles-derivatives

An article One-Pot Asymmetric Synthesis of Spiropyrazolone-Linked Cyclopropanes and Benzofurans through a General Michael Addition/Chlorination/Nucleophilic Substitution Sequence WOS:000481979200038 published article about N-HETEROCYCLIC CARBENE; ENANTIOSELECTIVE CONSTRUCTION; ORGANOCATALYSIS; PYRAZOLONES; ANNULATION; SCAFFOLDS; OXINDOLES; CATALYSIS in [Lu, Hong; Zhang, Huan-Xin; Tan, Chang-Yin; Liu, Jin-Yu; Xu, Peng-Fei] Lanzhou Univ, Sch Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China; [Lu, Hong; Wei, Hao] Northwest Univ, Coll Chem & Mat Sci, Natl Demonstrat Ctr Expt Chem Educ, Key Lab Synthet & Nat Funct Mol Chem,Minist Educ, Xian 710127, Shaanxi, Peoples R China in 2019, Cited 45. Category: pyrazoles-derivatives. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0

A sequential and general strategy has been successfully developed for the synthesis of spiropyrazolone scaffolds. This intriguing transformation of the asymmetric multicomponent catalysis process was realized with the combination of Michael addition/chlorination/nucleophilic substitution in a one-pot sequence, giving rise to a series of spiropyrazolones with fully substituted cyclopropanes and spiro-dihydrobenzofurans containing continuous stereogenic centers in good yields with excellent stereoselectivities.

Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.. Category: pyrazoles-derivatives

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Final Thoughts on Chemistry for C5H8N2

Safety of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Snyder, CJ; Wells, LA; Chavez, DE; Imler, GH; Parrish, DA or concate me.

An article Polycyclic N-oxides: high performing, low sensitivity energetic materials WOS:000459474300009 published article about FUSED HETEROCYCLE; CRYSTAL PACKING; CHEMISTRY; TETRAZINE; REDOX in [Snyder, Christopher J.; Wells, Lucille A.; Chavez, David E.] Los Alamos Natl Lab, Los Alamos, NM 87545 USA; [Imler, Gregory H.; Parrish, Damon A.] US Navy, Res Lab, Washington, DC 20375 USA in 2019.0, Cited 46.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Safety of 3,5-Dimethyl-1H-pyrazole

Polycyclic N-oxides were developed based on the heterocycles 1,2,4,5-tetrazine and 4H, 8H-difurazano[3,4-b:3′,4′-e]pyrazine. The new compounds are energetic and have excellent explosive properties, while maintaining low mechanical sensitivities. Most notably, compound 7 is thermally stable, insensitive, and has superior detonation properties to the state-of-the-art insensitive high explosive, 1,3,5-triamino-2,4,6-trinitrobenzene.

Safety of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Snyder, CJ; Wells, LA; Chavez, DE; Imler, GH; Parrish, DA or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

What unique challenges do researchers face in 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid

Computed Properties of C12H12N2O3. Bye, fridends, I hope you can learn more about C12H12N2O3, If you have any questions, you can browse other blog as well. See you lster.

An article A real-time data-based scan conversion method for single element ultrasound transducers WOS:000464437300004 published article about DECORRELATION; SPECKLE; TISSUE in [Csany, Gergely; Gyongy, Miklos] Pazmany Peter Catholic Univ, Fac Informat Technol & Bion, Budapest, Hungary; [Szalai, Klara] Semmelweis Univ, Dept Dermatol Venerol & Dermatooncol, Budapest, Hungary in 2019, Cited 42. The Name is 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Through research, I have a further understanding and discovery of 83-10-3. Computed Properties of C12H12N2O3

The current work investigates the performance of a real-time scan conversion algorithm for generating a 2-D ultrasound image from a laterally scanned single-element ultrasound transducer, which has applications in point-of-care devices such as for skin imaging. The algorithm employs a fixed calibration curve to update a predefined image grid in real time. Simulations showed that the calibration curve (with a maximum of 1) is robust to changes in scatterer concentration (8.3 x 10(-3) mean absolute error), signal to noise ratio (1.0 x 10(-3) mean absolute error for -5 dB SNR), and can be accurately predicted from a small number (31) of point scatterers (6.9 x 10(-3) mean absolute error). Good agreement was also found between the calibration curves obtained from simulated and experimental data (1.19 x 10(-2) mean absolute error). The scan conversion algorithm was validated by evaluation of the position estimation errors on both simulations and experiments. Clinical images of skin lesions (N = 20) demonstrate the feasibility of the algorithm for real, non-homogeneous tissue. Use of a fixed calibration curve compared to an adaptive calibration curve gave similar accuracies in the scanning step size range of 150-350 mu m (with an average overlap of the accuracy ranges of 92.94% for simulations and 42.83% for experiments), and a 350-fold improvement in computation time.

Computed Properties of C12H12N2O3. Bye, fridends, I hope you can learn more about C12H12N2O3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Get Up to Speed Quickly on Emerging Topics:67-51-6

COA of Formula: C5H8N2. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

COA of Formula: C5H8N2. Park, S; Lee, H; Lee, Y in [Park, Subin; Lee, Hanseul; Lee, Yunmi] Kwangwoon Univ, Dept Chem, Seoul 01897, South Korea published Copper-Catalyzed Regio- and Stereoselective 1,6-Conjugate Addition of Aza-Heterocycles to 1-Sulfonyl-1,3-dienes in 2020.0, Cited 63.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

An efficient and straightforward method for the synthesis of new and versatile sulfonyl-functionalized allylic amines through the selective copper-catalyzed aza-1,6-conjugate addition of heterocycles or arylamines to 1,4-disubstituted-1,3-dienyl sulfones has been developed. This catalytic process is promoted by a combination of an easily prepared and sterically demanding N-heterocyclic carbene-based copper complex and KOt-Bu under mild reaction conditions to provide a broad range of (E)-allylic amines with excellent regio- and stereoselectivities.

COA of Formula: C5H8N2. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Machine Learning in Chemistry about C5H8N2

Name: 3,5-Dimethyl-1H-pyrazole. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

Recently I am researching about C-H AMINATION; CARBON-NITROGEN BONDS; 1-NAPHTHYLAMINE DERIVATIVES; 8-AMINOQUINOLINE AMIDES; C5-H PHOSPHONATION; ARYL HALIDES; ACTIVATION; QUINOLINES; STRATEGY; SCOPE, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21102134, 21172200]. Name: 3,5-Dimethyl-1H-pyrazole. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Ma, YY; Shi, YQ; Yang, F; Wu, YS; Wu, YJ. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

A practical and efficient protocol for Ag/Ru-cocatalyzed regioselective C-H amination of 8-hydroxyquinoline esters with pyrazoles was developed, This reaction proceeded smoothly via a photoredox-mediated direct C-H/N-H oxidative coupling process. The remarkable features of this reaction include the wide substrate scope, mild reaction conditions and high regioselectivity at the C4 site of the quinolinyl moiety. (C) 2019 Elsevier Ltd. All rights reserved.

Name: 3,5-Dimethyl-1H-pyrazole. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Never Underestimate The Influence Of 67-51-6

Application In Synthesis of 3,5-Dimethyl-1H-pyrazole. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

An article Pyrazole ligands and their monometallic and bimetallic complexes: synthesis, characterization, and application as novel corrosion inhibitors WOS:000543657900001 published article about SOL-GEL COATINGS; MILD-STEEL; DERIVATIVES; ACID; PROTECTION in [Masoumi, Asad; Hossaini Sadr, Moayad; Soltani, Behzad] Azarbaijan Shahid Madani Univ, Dept Chem, Fac Sci, Tabriz, Iran in 2020.0, Cited 33.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

A series of pyrazole ligands named as 1,4-bis(3,5-dimethylpyrazol-1-yl)butane (bbd), 1,3-bis(3,5-dimethylpyrazol-1-yl)propane (bdpp), and 1,3-bis(3,5-dimethylpyrazol-1-yl)propane-2-ol (bdpo) along with their transition metal complexes including [Cu-2(mu(3)-SCN)(2)(mu-bbd)](n), [Cu-2(mu(3)-SCN)(2)(mu-bdpp)](n), and [Cu2Hg(mu(2)-SCN)(2)(bdpo)(2)(CH3COO)(2)](n)were synthesized and characterized using FT-IR and Uv-vis spectroscopies, as well as thermal gravimetric analysis. The prepared compounds were investigated as corrosion inhibitors to protect mild steel in 0.5 M H(2)SO(4)solution. Corrosion tests were performed by electrochemical impedance spectroscopy and potentiodynamic polarization measurements. The pyrazole ligands exhibited inhibition efficiencies in a range of 38-78%, which introduced them as moderate inhibitors. On the other hand, the pyrazole complexes showed inhibition efficiencies higher than 85%, demonstrating their high potentials to mitigate the steel corrosion. In addition, the bimetallic complex resulted in higher corrosion resistance than the two monometallic complexes. This was evidence of a critical role of the coordinated metal of the complex in forming an adhesive protection film on the steel surface.

Application In Synthesis of 3,5-Dimethyl-1H-pyrazole. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Why do aromatic interactions matter of compound:3-Methyl-1-p-tolyl-5-pyrazolone

COA of Formula: C11H12N2O. Welcome to talk about 86-92-0, If you have any questions, you can contact Changmai, S; Sultana, S; Sarma, B; Gogoi, S or send Email.

COA of Formula: C11H12N2O. I found the field of Chemistry very interesting. Saw the article Pd(ii)-Catalyzed alkyne annulation through allylic isomerization: synthesis of spiro-cyclopentadiene pyrazolones published in 2021, Reprint Addresses Gogoi, S (corresponding author), North East Inst Sci & Technol, CSIR, Chem Sci & Technol Div, Appl Organ Chem, Jorhat 785006, Assam, India.; Gogoi, S (corresponding author), AcSIR, Ghaziabad 201002, India.. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone.

The Pd(ii)-catalyzed activation of Csp(2)-H bond and double alkyne annulation which proceeds via allylic isomerization is reported for the first time. This reaction of antipyrines with alkynes provides an efficient synthetic route for the biologically important spiro-cyclopentadiene pyrazolones. In the presence of Lawesson’s reagent, this Pd(ii)-catalyzed annulation reaction affords another spiro-cyclopentadiene pyrazolone which displays very good fluorescence properties.

COA of Formula: C11H12N2O. Welcome to talk about 86-92-0, If you have any questions, you can contact Changmai, S; Sultana, S; Sarma, B; Gogoi, S or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics