Day: October 26, 2021

Recommanded Product: 86-92-0. Recently I am researching about MAGNESIUM-DL-ASPARTATE; P-TOLUIC ACID; MIXING PROPERTIES; ACTIVITY-COEFFICIENT; NRTL-SAC; 313.15 K; PREDICTION; INGREDIENTS; PARAMETERS, Saw an article supported by the Payame Noor University. Published in ELSEVIER in AMSTERDAM ,Authors: Akbari, F; Didehban, K; Farhang, M. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone

A new semi-theoretical equation is suggested for correlation of solid-liquid solubility data with temperature. The (solid + liquid) equilibrium for Terephthaldialdehyde, 4-Nitro-o-phennylenediamine, 2,4-dihydro- 5-methyl-2(4-methylphenyl)-3H-pyrazol-3-one (also named 1-(p-toly1)-3-methyl-5pyrazolone (PTMP)), 2-Amino-5-methylthiazole and 5-chloro-1-methyl-4-nitroimidazole in 18 solvents is correlated with semi-empirical models at temperatures T = 273.15 – 318.15 K under a pressure of 101.2 kPa. Moreover, a modified Apelblat model, lambda h model, Wilson model, NRTL model, new flexible equation as Akbari, Dideban and Farhang model (ADF) and for first time the modified Scatchard-Hildebrand equation were utilized to calculate the experiment values. The performance of both ADF and modified Scatchard-Hildebrand equation have been checked by calculating the solubility data with the AARD% of 1.3808% (for 775 data points) and 0.65% (for 100 data points), respectively. The Wilson model is applied to estimate the mixing Gibbs energy, mixing enthalpy, mixing entropy, activity coefficient (ln gamma(infinity)(1)) and reduced excess enthalpy (H-I(E,infinity)) at infinitesimal concentration were calculated.

Recommanded Product: 86-92-0. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Akbari, F; Didehban, K; Farhang, M or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Quality Control of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. In 2019 JMIR MHEALTH UHEALTH published article about HEART-RATE-VARIABILITY; WORK-LIFE BALANCE; BURNOUT; SURGEONS; STRESS; SATISFACTION; TONE in [Peters, Gregory Andrew; Wong, Matthew L.; Joseph, Joshua W.; Sanchez, Leon D.] Beth Israel Deaconess Med Ctr, Dept Emergency Med, 1 Deaconess Rd, Boston, MA 02215 USA; [Peters, Gregory Andrew; Wong, Matthew L.; Joseph, Joshua W.; Sanchez, Leon D.] Harvard Med Sch, Boston, MA 02115 USA in 2019, Cited 40. The Name is 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Through research, I have a further understanding and discovery of 83-10-3.

Background: The high prevalence of physician burnout, particularly in emergency medicine, has garnered national attention in recent years. Objective means of measuring stress while at work can facilitate research into stress reduction interventions, and wearable photoplethysmography (PPG) technology has been proposed as a potential solution. However, the use of low-burden wearable biosensors to study training and clinical practice among emergency physicians (EP) remains untested. Objective: This pilot study aimed to (1) determine the feasibility of recording on-shift photoplethysmographic data from EP, (2) assess the quality of these data, and (3) calculate standard pulse rate variability (PRV) metrics from the acquired dataset and examine patterns in these variables over the course of an academic year. Methods: A total of 21 EP wore PPG biosensors on their wrists during clinical work in the emergency department during a 9-hour shift. Recordings were collected during the first quarter of the academic year, then again during the fourth quarter of the same year for comparison. The overall rate of usable data collection per time was computed. Standard pulse rate (PR) and PRV metrics from these two time points were calculated and entered into Student t tests. Results: More than 400 hours of data were entered into these analyses. Interpretable data were captured during 8.54% of the total recording time overall. In the fourth quarter of the academic year compared with the first quarter, there was no significant difference in median PR (75.8 vs 76.8; P=.57), mean R-R interval (0.81 vs 0.80; P=.32), SD of R-R interval (0.11 vs 0.11; P=.93), root mean square of successive difference of R-R interval (0.81 vs 0.80; P=.96), low-frequency power (3.5×103 vs 3.4×103; P=.79), high-frequency power (8.5×103 vs 8.3×103; P=.91), or low-frequency to high-frequency ratio (0.42 vs 0.41; P=.43), respectively. Power estimates for each of these tests exceeded .90. A secondary analysis of the resident-only subgroup similarly showed no significant differences over time, despite power estimates greater than .80. Conclusions: Although the use of PPG biosensors to record real-time physiological data from EP while providing clinical care seems operationally feasible, this study fails to support the notion that such an approach can efficiently provide reliable estimates of metrics of interest. No significant differences in PR or PRV metrics were found at the end of the year compared with the beginning. Although these methods may offer useful applications to other domains, it may currently have limited utility in the contexts of physician training and wellness.

Quality Control of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. About 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid, If you have any questions, you can contact Peters, GA; Wong, ML; Joseph, JW; Sanchez, LD or concate me.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

An article Photocatalytic three-component asymmetric sulfonylation via direct C(sp(3))-H functionalization WOS:000642744500008 published article about C-H FUNCTIONALIZATION; STEREOSELECTIVE FUNCTIONALIZATION; SULFUR-DIOXIDE; ALKYLATION; CATALYST; ORGANOCATALYSIS; BORYLATION; ALLYLATION; INHIBITOR; ARYLATION in [Cao, Shi; Hong, Wei; Ye, Ziqi; Gong, Lei] Xiamen Univ, Coll Chem & Chem Engn, iChEM, Key Lab Chem Biol Fujian Prov, Xiamen, Fujian, Peoples R China in 2021.0, Cited 80.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Name: 3,5-Dimethyl-1H-pyrazole

The direct and selective C(sp(3))-H functionalization of cycloalkanes and alkanes is a highly useful process in organic synthesis owing to the low-cost starting materials, the high step and atom economy. Its application to asymmetric catalysis, however, has been scarcely explored. Herein, we disclose our effort toward this goal by incorporation of dual asymmetric photocatalysis by a chiral nickel catalyst and a commercially available organophotocatalyst with a radical relay strategy through sulfur dioxide insertion. Such design leads to the development of three-component asymmetric sulfonylation involving direct functionalization of cycloalkanes, alkanes, toluene derivatives or ethers. The photochemical reaction of a C(sp(3))-H precursor, a SO2 surrogate and a common alpha,beta-unsaturated carbonyl compound proceeds smoothly under mild conditions, delivering a wide range of biologically interesting alpha-C chiral sulfones with high regio- and enantioselectivity (>50 examples, up to >50:1 rr and 95% ee). This method is applicable to late-stage functionalization of bioactive molecules, and provides an appealing access to enantioenriched compounds starting from the abundant hydrocarbon compounds. The direct and selective C(sp(3))-H functionalization of cycloalkanes and alkanes is useful in organic synthesis but its application to asymmetric catalysis has been less explored. Here, the authors demonstrate the incorporation of a dual asymmetric photocatalyst which leads to the development of asymmetric sulfonylation involving direct functionalization of cycloalkanes, alkanes, toluene derivatives or ethers.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Cao, S; Hong, W; Ye, ZQ; Gong, L or concate me.. Name: 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Application In Synthesis of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Ardalan, A; Yusefi, H; Rouhi, N; Banar, A; Sohrabizadeh, S in [Ardalan, Ali; Yusefi, Homa] Univ Tehran Med Sci, Sch Publ Hlth, Dept Disaster & Emergency Hlth, Tehran, Iran; [Ardalan, Ali] Harvard Univ, Harvard Humanitarian Initiat, Cambridge, MA 02138 USA; [Yusefi, Homa; Rouhi, Narges; Banar, Ahad] Minist Hlth & Med Educ, Dept Publ Hlth, Disaster Risk Management Off, Tehran, Iran; [Sohrabizadeh, Sanaz] Shahid Beheshti Univ Med Sci, Sch Publ Hlth & Safety, Dept Hlth Disasters & Emergencies, Tehran, Iran published Household disaster preparedness in the Islamic Republic of Iran: 2015 estimation in 2020, Cited 25. The Name is 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Through research, I have a further understanding and discovery of 83-10-3.

Background: The Islamic Republic of Iran is at high risk of natural disasters. Households are the basic unit of society and they need to be prepared for disasters. Aims: This study assessed disaster preparedness among Iranian households in 2015. Methods: Using multistage cluster sampling, 2968 households in the catchment area of 53 public health departments in all 30 provinces of the Islamic Republic of Iran were surveyed on the disaster preparedness measures they had taken in the past year. The data collection questionnaire included 15 disaster preparedness measures. The mean preparedness score was calculated and its association with residence (urban versus rural), house ownership (owner versus renter) and education level of the head of the household (illiterate, elementary school, middle school, high school, university) was evaluated. Results: The mean score for household disaster preparedness was 9.3 out of 100 (95% confidence interval: 8.3-10.3). Multivariate analysis showed higher preparedness among rural than urban households (P = 0.02). Higher education level was positively associated with a higher preparedness score (P < 0.001), as was house ownership (P < 0.001). Conclusion: The level of household disaster preparedness in the Islamic Republic of Iran in 2015 was low. In line with the first priority for action of the Sendai Framework for Disaster Risk Reduction, the current study provides an overall picture of household disaster preparedness in the Islamic Republic of Iran. This estimation can be used as a baseline value for policy-making, planning, and evaluation of public awareness of disasters in the country. Application In Synthesis of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. About 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid, If you have any questions, you can contact Ardalan, A; Yusefi, H; Rouhi, N; Banar, A; Sohrabizadeh, S or concate me.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article One-Pot Asymmetric Synthesis of Spiropyrazolone-Linked Cyclopropanes and Benzofurans through a General Michael Addition/Chlorination/Nucleophilic Substitution Sequence published in 2019. Safety of 3-Methyl-1-p-tolyl-5-pyrazolone, Reprint Addresses Xu, PF (corresponding author), Lanzhou Univ, Sch Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China.. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone

A sequential and general strategy has been successfully developed for the synthesis of spiropyrazolone scaffolds. This intriguing transformation of the asymmetric multicomponent catalysis process was realized with the combination of Michael addition/chlorination/nucleophilic substitution in a one-pot sequence, giving rise to a series of spiropyrazolones with fully substituted cyclopropanes and spiro-dihydrobenzofurans containing continuous stereogenic centers in good yields with excellent stereoselectivities.

Safety of 3-Methyl-1-p-tolyl-5-pyrazolone. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Lu, H; Zhang, HX; Tan, CY; Liu, JY; Wei, H; Xu, PF or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Visible-Light Photoredox Catalyzed C-N Coupling of Quinoxaline-2(1H)-ones with Azoles without External Photosensitizer published in 2020.0. Recommanded Product: 67-51-6, Reprint Addresses Wang, L (corresponding author), Taizhou Univ, Adv Res Inst, Taizhou 318000, Zhejiang, Peoples R China.; Wang, L; Li, PH (corresponding author), Huaibei Normal Univ, Dept Chem, Huaibei 235000, Anhui, Peoples R China.; Wang, L; Li, PH (corresponding author), Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

A visible-light photoredox catalyzed C-N coupling of quinoxaline-2(1H)-ones with azoles in the absence of external photosensitizer has been developed. The protocol employs commercially available pyrazoles and triazoles as amination reagents and shows wide substrate scope, providing the corresponding C3-position amination products in good yields and high regioselectivity under ambient conditions. Investigations indicate that the starting materials and products can act as photosensitizers avoiding use of additional photocatalyst in an autocatalytic manner. In addition,(1)O(2)coexists with O(2)(.-)from molecular oxygen (O-3(2)) via an energy transfer (ET) and single electron transfer (SET) process during the reaction.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Sun, ML; Wang, L; Zhao, LL; Wang, ZM; Li, PH or concate me.. Recommanded Product: 67-51-6

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

HPLC of Formula: C12H12N2O3. Authors Milne, IA; Graham, JMR in CAMBRIDGE UNIV PRESS published article about in [Milne, I. A.] Univ Western Australia, Oceans Grad Sch, Crawley 6009, Australia; [Graham, J. M. R.] Imperial Coll London, Dept Aeronaut, London SW7 2AZ, England in 2019, Cited 13. The Name is 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Through research, I have a further understanding and discovery of 83-10-3

The changes in spectra and intensities of the streamwise component of turbulent velocity are calculated in the inflow of a turbine rotor. The flow is initially calculated in the limit when the turbulence is of small scale compared with the rotor diameter. Rapid distortion theory (RDT), Batchelor & Proudman (Q. J. Mech. Appl. Maths, vol. 7 (1), 1954, pp. 83-103) (BP), for small-scale turbulence is combined with the effect of the fluctuating potential flow field on the turbulence caused by the direct interaction of the incident turbulence with the rotor as a sheet of resistance. A second computation is then carried out for turbulence of larger length scale. The results of the calculations are compared with velocity measurements in the inflow of both a commercial wind turbine and a tidal turbine rotor.

HPLC of Formula: C12H12N2O3. About 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid, If you have any questions, you can contact Milne, IA; Graham, JMR or concate me.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article A structural study of new tetrakis(1H-pyrazol-1-yl)methanes published in 2019.0. SDS of cas: 67-51-6, Reprint Addresses Alkorta, I (corresponding author), CSIC, Inst Quim Med, Juan Cierva 3, E-28006 Madrid, Spain.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

Tetrakis(1H-pyrazol-l-yl)methanes are very rare compounds of which only two are known: the unsubstituted 1 obtained classically by Wicket in 1937 from carbon tetrachloride and prepared again several times and the 3,5-dimethyl substituted 2 obtained serendipitously by Pombeiro in 2009. We have now extended this group to include four new derivatives 8, 9,11 and 12 bearing methyl groups. The X-ray crystal structure of the four compounds has been determined. They have been studied by NMR both in solution (H-1, C-13, N-15) and in the solid state (C-13 and N-15). DFT calculations of the six compounds (geometries, energies and absolute shieldings) have been used to discuss the experimental observations. (C) 2019 Elsevier Ltd. All rights reserved.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Silva, VLM; Silva, AMS; Claramunt, RM; Lopez, C; Sanz, D; Infantes, L; Lopez, AM; Reviriego, F; Alkorta, I; Elguero, J or concate me.. SDS of cas: 67-51-6

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Sustainable Synthetic Approach for (Pyrazol-4-ylidene) pyridines By Metal Catalyst-Free Aerobic C(sp(2))-C(sp(3)) Coupling Reactions between 1-Amino-2-imino-pyridines and 1-Aryl-5-pyrazolones WOS:000482176800041 published article about C-H; BIOLOGICAL EVALUATION; PHOTOREDOX CATALYSIS; IN-VITRO; ALPHA-GLUCOSIDASE; PYRAZOLE; DERIVATIVES; POTENT; INHIBITORS; DESIGN in [Ibrahim, Hamada Mohamed; Behbehani, Haider] Kuwait Univ, Fac Sci, Chem Dept, POB 5969, Safat 13060, Kuwait; [Ibrahim, Hamada Mohamed] Fayoum Univ, Fac Sci, Chem Dept, POB 63514, Al Fayyum, Egypt in 2019, Cited 99. Computed Properties of C11H12N2O. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0

A novel, metal catalyst-free, and efficient method has been developed for the synthesis of (pyrazol-4-ylidene) pyridine derivatives. The process involves dehydrogenative coupling of 1-amino-2-imino-pyridines with 1-aryl-5pyrazolone derivatives utilizing O-2 as the sole oxidant. The new method benefits from a high atom economy, efficiency, and substrate scope, as well as the simplicity of reaction and product purification procedures.

About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Ibrahim, HM; Behbehani, H or concate me.. Computed Properties of C11H12N2O

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Asymmetric Organocatalysis Combined with Palladium Catalysis: Synergistic Effect on Enantioselective Mannich/alpha-Allylation Sequential Reactions of Pyrazolones in Constructing Vicinal Quaternary Stereocenters published in 2019. COA of Formula: C11H12N2O, Reprint Addresses Huang, Y (corresponding author), Xinjiang Univ, Coll Chem & Chem Engn, Key Lab Oil & Gas Fine Chem, Minist Educ & Xinjiang Uyghur Autonomous Reg, Urumqi 830000, Xinjiang, Peoples R China.; Zhang, XL (corresponding author), Xinjiang Uygur Autonomous Reg Prod Qual Supervis, Urumqi 830000, Xinjiang, Peoples R China.. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone

In this letter, an efficient one-pot asymmetric sequential reaction is achieved by organo/transition metal relay catalysis in constructing two consecutive C-C bonds, which involves enantioselective amino squaramide catalytic Mannich-type addition of pyrazolones to isatin-derived ketimines and a subsequent palladium catalyzed diastereoselective allylic alkylation of pyrazolones with allylic acetates. An array of novel pyrazolone-aminooxindole-propylene structural motifs are obtained in a high level of yield and with excellent enantio- and diastereoselectivity (up to 95% yield, >20:1 dr, >99% ee). This methodology features the formation of vicinal quarternary carbon-stereocenters, and the second all-carbon tetrasubstituted stereogenic center is induced by joint action of the achiral palladium catalysis and the chiral environment generated from the Mannich step. Moreover, the usefulness of this methodology is highlighted by converting the allylic product into the carbonyl compound.

COA of Formula: C11H12N2O. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Wu, GX; Xu, HH; Liu, ZR; Liu, YH; Yang, X; Zhang, XL; Huang, Y or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics