The important role of 3,5-Dimethyl-1H-pyrazole

SDS of cas: 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Pistritto, VA; Schutzbach-Horton, ME; Nicewicz, DA or concate me.

SDS of cas: 67-51-6. I found the field of Chemistry very interesting. Saw the article Nucleophilic Aromatic Substitution of Unactivated Fluoroarenes Enabled by Organic Photoredox Catalysis published in 2020.0, Reprint Addresses Nicewicz, DA (corresponding author), Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole.

Nucleophilic aromatic substitution (SNAr) is a classical reaction with well-known reactivity toward electron-poor fluoroarenes. However, electron-neutral and electron-rich fluoro(hetero)arenes are considerably underrepresented. Herein, we present a method for the nucleophilic defluorination of unactivated fluoroarenes enabled by cation radical-accelerated nucleophilic aromatic substitution. The use of organic photoredox catalysis renders this method operationally simple under mild conditions and is amenable to various nucleophile classes, including azoles, amines, and carboxylic acids. Select fluorinated heterocycles can be functionalized using this method. In addition, the late-stage functionalization of pharmaceuticals is also presented. Computational studies demonstrate that the site selectivity of the reaction is dictated by arene electronics.

SDS of cas: 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Pistritto, VA; Schutzbach-Horton, ME; Nicewicz, DA or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An overview of features, applications of compound:3-Methyl-1-p-tolyl-5-pyrazolone

Recommanded Product: 86-92-0. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Zhang, Y; Nie, LJ; Luo, L; Mao, JX; Liu, JX; Xu, GH; Chen, DL; Luo, HQ or concate me.

Recently I am researching about HENRY NITROALDOL REACTIONS; ORGANIC-SYNTHESIS; ON-WATER; DERIVATIVES; ANTIPYRINE; ALCOHOLS; HETEROCYCLES; CHEMISTRY; CYCLIZATION; EFFICIENT, Saw an article supported by the Jiangxi Provincial Department of Science and Technology Fund [20192BAB213007]; Education Department of Jiangxi Province [G11170835]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21865003, 21763002]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Zhang, Y; Nie, LJ; Luo, L; Mao, JX; Liu, JX; Xu, GH; Chen, DL; Luo, HQ. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone. Recommanded Product: 86-92-0

The selective condensation of pyrazolones with isatins using water as the reaction medium is presented. This strategy provides an environmentally benign synthetic route to synthesize various potentially bioactive pyrazolone substituted oxindoles. (C) 2020 Elsevier Ltd. All rights reserved.

Recommanded Product: 86-92-0. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Zhang, Y; Nie, LJ; Luo, L; Mao, JX; Liu, JX; Xu, GH; Chen, DL; Luo, HQ or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Our Top Choice Compound:3,5-Dimethyl-1H-pyrazole

Quality Control of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Saldia, M; Guzman, N; Palominos, F; Sandoval-Altamirano, A; Gunther, G; Pizarro, N; Vega, A or concate me.

In 2019.0 ACS OMEGA published article about RHENIUM(I) TRICARBONYL COMPLEXES; BRIDGING 1,2-DIAZINE LIGANDS; RE-I COMPLEX; CRYSTAL-STRUCTURES; PHOTOCATALYTIC REDUCTION; COPPER(II) COMPLEXES; SINGLET OXYGEN; EXCITED-STATE; MAGNETOSTRUCTURAL CORRELATIONS; ORGANOMETALLIC COMPLEXES in [Saldia, Marianela; Guzman, Nicolas; Palominos, Franco; Sandoval-Altamirano, Atalina; Pizarro, Nancy; Vega, Andres] Univ Andres Bello, Fac Ciencias Exactas, Dept Ciencias Quim, Av Quillota 980, Vina Del Mar 2531015, Chile; [Gunther, German] Univ Chile, Fac Ciencias Quim & Farmaceut, Dept Quim Organ & Fisicoquim, Sergio Livingstone 1007, Santiago 8380492, Chile; [Vega, Andres] CEDENNA, Ctr Desarrollo Nanociencia & Nanotecnol, Santiago, Chile; [Saldia, Marianela] Univ Cent, Fac Ciencias Salud, Inst Invest & Innovac Salud, Lord Cochrane 417, Santiago 8330507, Chile in 2019.0, Cited 90.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Quality Control of 3,5-Dimethyl-1H-pyrazole

The direct reaction of a series of substituted (1H-pyrazol-1-yl)pyridazine (L-I: 6-(1H-pyrazolyl)pyridazine; L-II: 3-chloro-6-(1H-pyrazole-1-yl)-pyridazine; L-III: 6-(1H-3,5-dimethylpyrazolyl)pyridazine-3-carboxylic acid; L-IV: 3,6-bis-N-pyrazolyl-pyridazine; and L-V: 3,6-bis-N-3-methylpyrazolyl-pyridazine) with the bromotricarbonyl(tetrahydrofuran)rhenium(I) dimer leads to the monometallic complexes [(L-X)Re(CO)(3)Br] (I-V), which displays a nonregular octahedral geometry around the Re-I center and a fac-isomerism for the carbonyl groups, whereas pyridazine and pyrazolyl rings remain highly coplanar after coordination to rhenium. Cyclic voltammetry shows one irreversible oxidation and one irreversible reduction for each compound as measured in N, N-dimethylformamide. Oxidation ranges from 0.94 V for III to 1.04 V for I and have been attributed to the Re-I/Re-II couple. In contrast, the reductions are ligand centered, ranging from -1.64 V for II to -1.90 V for III and V. Density functional theory calculations on the vertical one electron oxidized and one electron reduced species, using the gas-phase optimized geometry for the neutral complex confirm this assignment. Compounds I-V show two absorption bands, one around 410 nm (metal-to-ligand charge transfer (MLCT), Re-d pi -> pi*) and the other at similar to 300 nm (intraligand, pi -> pi*). Excitation at 400 nm at 77 K leads to unstructured and monoexponential emission with large Stokes shift, whose maxima vary between 570 (III) and 636 (II) nm. The quantum yields for these emissions in solution are intensified strongly going from air to argon equilibrated solution. Singlet oxygen quantum yields change from 0.03 (III) to 0.21 (IV). These data are consistent with emission from (MLCT)-M-3. The emission undergoes a bathochromic shift when R-1 is a pi-donating group (Cl or N-pyrazolyl) and a hypsochromic shift for a pi-acceptor (COOH). The bimolecular emission quenching rate constant by triethylamine (TEA) for II, IV, and V is 1.09, 0.745, and 0.583 x 10(8) M-1 s(-1), respectively. Photolysis in dichloromethane-CO2 saturated solution with TEA as a sacrificial electron donor leads in all cases to formic acid generation.

Quality Control of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Saldia, M; Guzman, N; Palominos, F; Sandoval-Altamirano, A; Gunther, G; Pizarro, N; Vega, A or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

New explortion of 3-Methyl-1-p-tolyl-5-pyrazolone

Recommanded Product: 3-Methyl-1-p-tolyl-5-pyrazolone. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Zhu, YF; Wei, BL; Wei, JJ; Wang, WQ; Song, WB; Xuan, LJ or concate me.

Authors Zhu, YF; Wei, BL; Wei, JJ; Wang, WQ; Song, WB; Xuan, LJ in PERGAMON-ELSEVIER SCIENCE LTD published article about AGENTS; DERIVATIVES in [Zhu, Ye-Fu; Wei, Bo-Le; Wei, Jiao-Jiao; Wang, Wen-Qiong; Song, Wei-Bin; Xuan, Li-Jiang] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China; [Zhu, Ye-Fu; Wei, Bo-Le; Wei, Jiao-Jiao] Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China in 2019, Cited 18. Recommanded Product: 3-Methyl-1-p-tolyl-5-pyrazolone. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0

A palladium-catalyzed oxidative dehydrogenation reaction in the presence of AMS and base to synthesize pyrazolones and pyrazoles was identified. This method can be utilized to a wide range of substrates, operates under mild react conditions and can give high yields. We believe it could be used as an alternative protocol for the classical dehydrogenation reactions. (C) 2019 Published by Elsevier Ltd.

Recommanded Product: 3-Methyl-1-p-tolyl-5-pyrazolone. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Zhu, YF; Wei, BL; Wei, JJ; Wang, WQ; Song, WB; Xuan, LJ or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

An overview of features, applications of compound:67-51-6

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Shang, JF; Liu, QX; Wang, BL; Li, ZM or concate me.. Safety of 3,5-Dimethyl-1H-pyrazole

An article Synthesis and Biological Activities of Novel N-Substitutedphenyl-2-pyrazolylnicotinamides WOS:000469862900033 published article about INSECTICIDAL ACTIVITIES; ANTHRANILIC DIAMIDES; DESIGN; DERIVATIVES; SAR in [Shang, Junfeng; Liu, Qiaoxia; Wang, Baolei; Li, Zhengming] Nankai Univ, Coll Chem, State Key Lab Elementoorgan Chem, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China in 2019.0, Cited 18.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Safety of 3,5-Dimethyl-1H-pyrazole

Based on the agrochemical structure of anthranilic diamides, fourteen novel N-substittitedphenyl-2-pyrazolylnicotinamides were conveniently synthesized with 2-chloro-3-cyanopyridine and 4-bromopyrazole or 3,5-dimethylpyrazole as starting materials, via an acyl transposing design strategy. Their structures were characterized by 1H NMR, 13C NMR and HRMS. The preliminary bioassay tests indicated that most of these compounds exhibited obvious insecticidal activity at the test concentration of 200 mg/L, among which N-(4-chloro-2-(ethylcarbamoyl)-6-methylphenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)nicotinamide (II) possessed a 70% mortality rate against Mythimna separata Walker: some of the compounds displayed favorable fungicidal activities at 50 mg/L towards Physalospora piricola and Alternaria solani Sorauer, especially 2-(4-bromo-1H-pyrazol-1-yl)-N-(2-(cyclopropylcarbamoyl)-4-iodo-6-methylphenyl)nicotinamide (If) and 2-(4-bromo-1H-pyrazol-1-yl)-N-(4-chloro-2-(ethylcarbamoyl)-6-methylphenyl)nicotinamide (Ih) against Physalospora piricola, and 2-(4-bromo-1H-pyrazol-1-yl)-N-(4-chloro-2-(propylcarbamoyl)phenyl)nicotinamide (Id) against Alternaria solani Sorauer had growth inhibitory rates of 62.9%, 54.3% and 54.5%, respectively. These research results provide important reference for the further study of novel 2-pyrazolylnicotinamide derivatives.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Shang, JF; Liu, QX; Wang, BL; Li, ZM or concate me.. Safety of 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

More research is needed about 3,5-Dimethyl-1H-pyrazole

Safety of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Shirshin, KK; Esipovich, AL; Kazantsev, OA; Rumyantsev, M; Korotaev, MS; Rogozhin, AE or concate me.

Authors Shirshin, KK; Esipovich, AL; Kazantsev, OA; Rumyantsev, M; Korotaev, MS; Rogozhin, AE in WILEY-V C H VERLAG GMBH published article about NUCLEOPHILIC REACTIONS; TERTIARY-AMINES; CATALYSTS; OPTIMIZATION; AMMONIOLYSIS; AMINOLYSIS; ALKYLATION; ALCOHOLS; MODEL in [Shirshin, Konstantin K.; Esipovich, Anton L.; Kazantsev, Oleg A.; Rumyantsev, Misha; Korotaev, Mikhail S.; Rogozhin, Anton E.] Nizhnii Novgorod State Tech Univ, 24 Ulitsa Minina Minin St, Nizhnii Novgorod, Russia in 2021.0, Cited 54.0. Safety of 3,5-Dimethyl-1H-pyrazole. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

Comparison of various organic compounds such as glycols, amines and alkanolamines as organocatalysts in amidation of fatty acid methyl esters with 3-(dimethylamino)-1-propylamine was made for the first time. It was experimentally detected that catalysts containing OH-groups (alcohols, glycols, glycerol and aminoalcohols) influence the reaction rate. Moreover, catalytic effect is depending on the catalysts geometry significantly. 1,5-diols (e. g. diethylene glycol and diethanolamine) were found to accelerate the reaction more than other OH-groups containing additives. It was supposed, that this catalytic effect is caused by specific associative interactions between reactants and 1,5-diols, what was confirmed by quantum mechanics calculations. Catalysts concentration effects on the reaction rate were also investigated.

Safety of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Shirshin, KK; Esipovich, AL; Kazantsev, OA; Rumyantsev, M; Korotaev, MS; Rogozhin, AE or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

The Absolute Best Science Experiment for 3-Methyl-1-p-tolyl-5-pyrazolone

About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Zhang, QD; Zhao, BL; Li, BY; Du, DM or concate me.. COA of Formula: C11H12N2O

An article Squaramide-catalyzed asymmetric Mannich reactions between 3-fluorooxindoles and pyrazolinone ketimines WOS:000477986000013 published article about CHIRAL SQUARAMIDE; MICHAEL ADDITION; DERIVATIVES; INHIBITORS; PYRAZOLIN-5-ONES; CONSTRUCTION; PYRAZOLONES in [Zhang, Qing-Da; Zhao, Bo-Liang; Li, Bing-Yu; Du, Da-Ming] Beijing Inst Technol, Sch Chem & Chem Engn, 5 South Zhongguancun St, Beijing 100081, Peoples R China in 2019, Cited 28. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0. COA of Formula: C11H12N2O

An enantioselective Mannich reaction between 3-fluorooxindoles and pyrazolinone ketimines has been developed for the construction of amino-pyrazolone-oxindoles containing stereogenic C-F units. Based on this new protocol that allows for the generation of two adjacent tetrasubstituted stereocenters, a variety of structurally diverse fluorinated amino-pyrazolone-oxindoles were obtained in good to excellent yields with excellent diastereoselectivities and enantioselectivities (up to 98% yield, >20 : 1 dr and >99% ee). What’s more, good yield and high stereoselectivities were obtained in the gram-scale reaction.

About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Zhang, QD; Zhao, BL; Li, BY; Du, DM or concate me.. COA of Formula: C11H12N2O

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

New learning discoveries about C5H8N2

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Li, GB; Field, JA; Zeng, C; Madeira, CL; Nguyen, CH; Jog, KV; Speed, D; Sierra-Alvarez, R or concate me.. Category: pyrazoles-derivatives

An article Diazole and triazole inhibition of nitrification process in return activated sludge WOS:000509791600086 published article about CORROSION-INHIBITORS; WASTE-WATER; TOXICITY; OXIDE; SOIL in [Li, Guangbin; Field, James A.; Zeng, Chao; Madeira, Camila Leite; Chi Huynh Nguyen; Jog, Kalyani Vikas; Sierra-Alvarez, Reyes] Univ Arizona, Dept Chem & Environm Engn, POB 210011, Tucson, AZ 85721 USA; [Speed, David] GLOBALFOUNDRIES, Hopewell Jct, NY USA in 2020.0, Cited 40.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Category: pyrazoles-derivatives

Azoles are emerging contaminants that are resistant to biodegradation during wastewater treatment. Their presence has been widely reported in wastewater effluents and receiving waters. In this work, the potential inhibition of nitrification process by six different azole compounds in wastewater treatment plants was investigated in batch bioassays. The azoles studied included three diazoles: pyrazole (Pz); 1-methylpyrazole (MePz); 3,5-dimethylpyrazole (DMePz); and three triazoles: 1,2,4-triazole (Tz); benzotriazole (BTz); and 5-methyl benzotriazole (MeBTz). The concentration of azoles causing 50% inhibition (IC50) increased (azoles became less inhibitory) in the following order (mg L-1): BTz (1.99) < MeBTz (218) < Pz (2.69) < Tz (3.53) < DMePz (17.3) < MePz (49.6). No clear structure-inhibitory relationships were found using Log P and pKa as structural properties. The toxicity of any given azole may be related to the role of substituent groups on disabling/enabling binding to the active sites of metallo-enzymes in nitrifying microorganisms. This is exemplified by the low toxicity of MePz, which has a cyclic N blocked by a methyl group. The observed inhibition caused to nitrifying bacteria is more severe than their cytotoxicity to other target organisms (e.g., methanogens and heterotrophic bacteria), suggesting a specific inhibition to the copper-containing enzyme, ammonium monooxygenase, in ammonia oxidizing nitrifying microorganisms. (C) 2019 Elsevier Ltd. All rights reserved. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Li, GB; Field, JA; Zeng, C; Madeira, CL; Nguyen, CH; Jog, KV; Speed, D; Sierra-Alvarez, R or concate me.. Category: pyrazoles-derivatives

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An overview of features, applications of compound:67-51-6

SDS of cas: 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Glukhacheva, VS; Il’yasov, SG; Kazantsev, IV; Shestakova, EO; Il’yasov, DS; Eltsov, IV; Nefedov, AA; Gatilov, YV or concate me.

Authors Glukhacheva, VS; Il’yasov, SG; Kazantsev, IV; Shestakova, EO; Il’yasov, DS; Eltsov, IV; Nefedov, AA; Gatilov, YV in AMER CHEMICAL SOC published article about ANTIBACTERIAL; ANTIFUNGAL; COMPLEXES; SERIES; ACID in [Glukhacheva, Vera S.; Il’yasov, Sergey G.; Kazantsev, Igor, V; Shestakova, Elena O.; Il’yasov, Dmitri S.] Russian Acad Sci IPCET SB RAS, Inst Problems Chem & Energet Technol, Siberian Branch, Biisk 659322, Russia; [Eltsov, Ilia, V; Nefedov, Andrey A.] Novosibirsk State Univ, Novosibirsk 630090, Russia; [Nefedov, Andrey A.; Gatilov, Yuri, V] Russian Acad Sci NIOCh SB RAS, Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia in 2021.0, Cited 40.0. SDS of cas: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

A new approach is suggested herein for the synthesis of pyrazole derivatives by reacting 4-nitrosemicarbazide with acetylacetone. Additional studies were done on the reaction of acetylacetone with semicarbazide and its derivatives (4-aminosemicarbazide, methylsemicarbazide, and dimethylsemicarbazide). The study on the reaction with acetylacetone resulted in monocyclic 3,5-dimethyl-N-nitropyrazole-1-carboxamide, monocyclic 5-hydroxy-3,5-dimethyl-2-pyrazoline, and bicyclic bis(3,5-dimethylpyrazole-1-carbonyl)hydrazine, and conditions for the formation of acetone semicarbazone were identified. The structures of the resultant compounds were validated by physicochemical analytical methods, including X-ray diffraction. The computer-aided screening in the PASS prediction software discovered a high biological activity of the newly obtained compounds.

SDS of cas: 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Glukhacheva, VS; Il’yasov, SG; Kazantsev, IV; Shestakova, EO; Il’yasov, DS; Eltsov, IV; Nefedov, AA; Gatilov, YV or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

The Absolute Best Science Experiment for C11H12N2O

About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Shaikh, I; Jadeja, RN; Patel, R or concate me.. Formula: C11H12N2O

In 2020 POLYHEDRON published article about DNA-BINDING; PLASMODIUM-FALCIPARUM; COPPER(II) COMPLEXES; CU(II) COMPLEXES; DERIVATIVES; ANTICANCER; BINARY in [Shaikh, Irfan; Jadeja, R. N.] Maharaja Sayajirao Univ Baroda, Fac Sci, Dept Chem, Vadodara 390002, India; [Patel, Rajesh] Veer Narmad South Gujarat Univ, Dept Biosci, Surat 395007, India in 2020, Cited 33. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0. Formula: C11H12N2O

Three novel mixed ligand Zn(II) complexes {complex 1 = [Zn(L1)(2)(bpy)], complex 2 = [Zn(L2)(2)(bPY)], complex 3 = [Zn(L2)(2)(phen)], where bpy = 2,2′-bipyridine and phen = 1,10-phenanthroline} of 4-(4-chlorobenzoyl)-2-(3-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one (HL1) and 4-(4-chlorobenzoyl)-5-methyl-2-(p-tolyl)-2,4-dihydro-3H-pyrazol-3-one (HL2) were synthesized and characterized by H-1 and C-13 NMR, FTIR, TG-DTA, UV-Vis, elemental analysis, molar conductance and single crystal X-ray structure determination. Based on analytical and spectroscopic techniques, all the three Zn(II) complexes were found to have a distorted octahedral geometry. The ligands and the complexes were screened for antimalarial activity against plasmodium falciparum. The zinc(II) complexes showed greater antimalarial activity than their parent ligands. (C) 2020 Elsevier Ltd. All rights reserved.

About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Shaikh, I; Jadeja, RN; Patel, R or concate me.. Formula: C11H12N2O

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics