Category: 4551-69-3

Tereshchenkova, Anna A. published the artcileSolid-phase extraction of lanthanum on modified low-polarity sorbents, Product Details of C17H14N2O2, the publication is Vestnik Moskovskogo Universiteta, Seriya 2: Khimiya (2013), 54(4), 203-209, database is CAplus.

Preconcentration of lanthanum on various low-polarity sorbents (hexadecyl-silica, hyper cross-linked polystyrene, polyvinylidene difluoride, activated carbon) dynamically coated with 1-phenyl-3-methyl-4-benzoylpyrazol-5-one (PMBP) was studied. Reagent and lanthanum distribution coefficients were evaluated under dynamic conditions. Reagent elution was studied. Recovery of lanthanum with coated and uncoated sorbents was studied. Efficiency of desorption with nitric acid solutions or ethanol was studied.

Vestnik Moskovskogo Universiteta, Seriya 2: Khimiya published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C10H10N2, Product Details of C17H14N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Arkhipova, A. A. published the artcileDifferent Approaches to Solid-Phase Extraction of Lanthanum with Low-Polar Sorbents: Comparison of Dynamic Coating, Impregnation and On-Line Mixing, SDS of cas: 4551-69-3, the publication is Separation Science and Technology (Philadelphia, PA, United States) (2015), 50(5), 729-734, database is CAplus.

Three different approaches to preconcentration of metal ions using low-polar sorbents were compared: dynamic coating of the sorbent surface with hydrophobic chelating reagent; impregnation of the sorbent with a solution of the reagent in a suitable volatile organic solvent; and online merging of sample and reagent streams prior to solid-phase extraction of metal-reagent complexes. Lanthanum was used as a model analyte; 1-phenyl-3-methyl-4-benzoylpyrazol-5-one (PMBP) as a reagent for preconcentration It was found out that the most effective approach for the analyte recovery from a large sample volume is the use of a dynamically coated sorbent with high sp. surface.

Separation Science and Technology (Philadelphia, PA, United States) published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, SDS of cas: 4551-69-3.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Pettinari, Riccardo published the artcileCytotoxicity of Ruthenium-Arene Complexes Containing β-Ketoamine Ligands, Product Details of C17H14N2O2, the publication is Organometallics (2013), 32(1), 309-316, database is CAplus.

New ruthenium(II) arene derivatives (arene = p-cymene, benzene, hexamethylbenzene) containing β-ketoamine ligands L’ (HL’ in general; in detail, HL^ph,ph = (4Z)-3-methyl-4-((phenylamino)(phenyl)methylene)-1-phenyl-1H-pyrazol-5(4H)-one, HL^naph,ph = (4Z)-3-methyl-4-((phenyamino)(naphthalen-2-yl)methylene)-1-phenyl-1H-pyrazol-5(4H)-one, HL^et,ph = (4Z)-3-methyl-4-(1-(phenylamino)propylidene)-1-phenyl-1H-pyrazol-5(4H)-one) have been synthesized and characterized by spectroscopy (IR, ESI-MS, ¹H and ¹³C NMR) and elemental anal. The ligands in the anionic form coordinate ruthenium in a chelating κ²N,O-bidentate fashion, affording 1:1 derivatives of the formula [Ru(arene)(L’)Cl]. Further reaction of [Ru(p-cymene)(L’)Cl] with AgPF₆ or PTA (PTA = 1,3,5-triaza-7-phosphaadamantane) in methanol affords [Ru(p-cymene)(L’)(CH₃OH)][PF₆] and [Ru(p-cymene)(L’)(PTA)]Cl, resp. The solid-state structures of the ligand HL^et,ph and complexes [Ru(p-cymene)(L^ph,ph)Cl], [Ru(p-cymene)(L^naph,ph)Cl], and [Ru(p-cymene)(L^et,ph)Cl] have been determined by single-crystal x-ray diffraction. The antitumor activity of both the ligands and complexes has been evaluated against the human ovarian carcinoma cell line A2780 and its cisplatin-resistant equivalent A2780R, some of the complexes showing significant cytotoxicity toward the cisplatin-resistant cell line.

Organometallics published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Product Details of C17H14N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Chumakov, Yu. M. published the artcileCrystal structure of bis(4-benzoyl-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-onato)-(ethanol)-dioxourane(VI) ethanol solvate, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is Journal of Structural Chemistry (2014), 55(6), 1116-1119, database is CAplus.

The crystal structure of bis(4-benzoyl-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-onato)-(EtOH)-dioxourane(VI) EtOH solvate [UO₂L₂(EtOH)]·EtOH (I), where HL is 4-benzoyl-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one, is determined The asym. part on the unit cell of the crystal structure of I contains the complex of uranyl ion with two bidentately coordinated L^– ions and coordinated mol. of EtOH. In the outer coordination sphere of the central atom, the solvated EtOH mol. is located. The coordination polyhedron of the U atom in complex I is a pentagonal bipyramid. Its equatorial plane is composed of O atoms of HL and EtOH. In the axial positions of the metal coordination polyhedron the O atoms are located. In the crystal, the complexes of the studied compound are linked together via H bonds of the outer-sphere EtOH mol. in chains along the [100] direction. Between the chains in the crystal, the van der Waals interaction occurs.

Journal of Structural Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Asegbeloyin, J. N. published the artcileSynthesis, characterization and antimicrobial screening of some 4-acylpyrazoloimines and some 3d transition metal(II) complexes, Quality Control of 4551-69-3, the publication is Asian Journal of Chemistry (2014), 26(9), 2753-2758, database is CAplus.

Some acylhydroxypyrazole acylhydrazones, e.g., I (R = pentyl, Pr), and their 3d transition metal(II) complexes were synthesized. The ligands and their 3d transition metal complexes were characterized by elemental anal., molar conductance, magnetic susceptibility measurements and spectroscopic methods. The ligands behaved as mono-anion ONO or ONS donor mols. Microanal., electronic spectral and magnetic measurements showed the metal complexes as ML₂ type. All the synthesized compounds were screened for their in vitro antimicrobial activity against some gram pos. and gram neg. clin. bacterial strains. Antimicrobial activity test results showed that the metallic derivatives are more active against the bacterial strains than the imines.

Asian Journal of Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Quality Control of 4551-69-3.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

De Pascali, Sandra A. published the artcileSynthesis, Crystal Structure, and Biological Study of Pt^II Complexes with 4-Acyl-5-pyrazolones, Product Details of C17H14N2O2, the publication is European Journal of Inorganic Chemistry (2014), 2014(7), 1249-1259, database is CAplus.

The syntheses of new Pt^II complexes with 4-acyl-5-pyrazolones [HQ^Ph = 1-phenyl-3-methyl-4-benzoylpyrazol-5-one, a; HQ^py,CF3 = 1-(2-pyridyl)-3-methyl-trifluoroacetylpyrazol-5-one, b] are reported: trans-[PtCl₂(DMSO)(HQ^Ph)] (1a), cis-[PtCl₂(DMSO)(HQ^Ph)] (2a), [PtCl(DMSO)(Q^py,CF3)] (1b), and [PtCl₂(KQ^py,CF3)] (2b). All complexes were characterized by multinuclear (¹H, ¹³C, ¹⁹F, and ¹⁹⁵Pt), multidimensional NMR spectroscopy and single-crystal x-ray diffraction analyses. The isomer trans-[PtCl₂(DMSO)(HQ^Ph)] (1a) crystallizes in two polymorphic forms, which correspond to two different conformers. In the trans-syn conformer (1a_M) (monoclinic, space group P2₁/c), the H atom of the enol group [O(1)H(1)] establishes an intramol. hydrogen bond with the ketone oxygen (O2), whereas in the trans-anti conformer (1a_O) (orthorhombic, space group Pca2₁), the same groups are involved in an analogous intermol. H bond. Interestingly, the cis isomer (2a) showed in solution and at room temperature slow rotation around both the Pt-N1 and the Pt-S bonds, which restrained both the acylpyrazolone and DMSO ligand motion. Moreover, the water solubility of the complexes trans- and cis-[PtCl₂(DMSO)(HQ^Ph)] (1a and 2a) and [PtCl₂(KQ^py,CF3)] (2b) allowed to perform in vitro biol. assays on platinum-sensitive human endometrium (HeLa) and platinum-resistant human breast (MCF-7) cancer cell lines. It was also possible to compare their cytotoxicity to cisplatin. Interestingly, trans isomer 1a showed higher cytotoxicity on HeLa cells compared to the cis isomer 2a.

European Journal of Inorganic Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Product Details of C17H14N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

De Pascali, Sandra A. published the artcileSynthesis, Crystal Structure, and Biological Study of Pt^II Complexes with 4-Acyl-5-pyrazolones, Product Details of C17H14N2O2, the publication is European Journal of Inorganic Chemistry (2014), 2014(7), 1249-1259, database is CAplus.

The syntheses of new Pt^II complexes with 4-acyl-5-pyrazolones [HQ^Ph = 1-phenyl-3-methyl-4-benzoylpyrazol-5-one, a; HQ^py,CF3 = 1-(2-pyridyl)-3-methyl-trifluoroacetylpyrazol-5-one, b] are reported: trans-[PtCl₂(DMSO)(HQ^Ph)] (1a), cis-[PtCl₂(DMSO)(HQ^Ph)] (2a), [PtCl(DMSO)(Q^py,CF3)] (1b), and [PtCl₂(KQ^py,CF3)] (2b). All complexes were characterized by multinuclear (¹H, ¹³C, ¹⁹F, and ¹⁹⁵Pt), multidimensional NMR spectroscopy and single-crystal x-ray diffraction analyses. The isomer trans-[PtCl₂(DMSO)(HQ^Ph)] (1a) crystallizes in two polymorphic forms, which correspond to two different conformers. In the trans-syn conformer (1a_M) (monoclinic, space group P2₁/c), the H atom of the enol group [O(1)H(1)] establishes an intramol. hydrogen bond with the ketone oxygen (O2), whereas in the trans-anti conformer (1a_O) (orthorhombic, space group Pca2₁), the same groups are involved in an analogous intermol. H bond. Interestingly, the cis isomer (2a) showed in solution and at room temperature slow rotation around both the Pt-N1 and the Pt-S bonds, which restrained both the acylpyrazolone and DMSO ligand motion. Moreover, the water solubility of the complexes trans- and cis-[PtCl₂(DMSO)(HQ^Ph)] (1a and 2a) and [PtCl₂(KQ^py,CF3)] (2b) allowed to perform in vitro biol. assays on platinum-sensitive human endometrium (HeLa) and platinum-resistant human breast (MCF-7) cancer cell lines. It was also possible to compare their cytotoxicity to cisplatin. Interestingly, trans isomer 1a showed higher cytotoxicity on HeLa cells compared to the cis isomer 2a.

European Journal of Inorganic Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Product Details of C17H14N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Wu, Xiren published the artcileSynthesis, characterization and antibacterial activity of taurine PMBP schiff base and their metal complexes, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is Guangdong Weiliang Yuansu Kexue (2013), 20(4), 18-22, database is CAplus.

Objective: Synthesis of novel taurine schiff base and its metal complexes, and study on the antibacterial activities. Method: The schiff base is dissolved in absolute Me alc., and mixed with four kinds of Zn(II), Co(II), Ni(II), Cu(II) metal acetate sep. After heating under reflux, filtration and drying, we get the target compounds The element anal., IR spectra and molar conductance were used to analyze the structure and composition of the schiff base and its Zn(II), Co(II), Ni(II), Cu(II) complexes. The drilling method is used to examine the complexes antibacterial activities. Result: Four kinds of complexes M(L)(H₂O)_2∼3 belong to 1:1 non-electrolyte. The primary biol. activity assay showed that all products exhibited medium to high antibacterial activities against E. coli and Streptococcus pneumoniae, among which the Cu(II) and Co(II) complexes of the schiff base gave the strongest activity which is better than that of the schiff base. Conclusion: The preparation of the taurine-PMBP metal complex provides new content for the coordination chem. Good antibacterial activity provides the basis for its application in medicine.

Guangdong Weiliang Yuansu Kexue published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C6H8O4, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Xu, Li-Ying published the artcile(4Z)-4-[(2-Chloroanilino)(phenyl)methylidene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one, Synthetic Route of 4551-69-3, the publication is Acta Crystallographica, Section E: Structure Reports Online (2012), 68(6), o1843, database is CAplus and MEDLINE.

The title compound, C₂₃H₁₈ClN₃O, exists in an enamine-keto form with the amino group involved in an intramol. N-H···O hydrogen bond. The five-membered ring is nearly planar, the largest deviation being 0.0004 (7) Å, and makes dihedral angles of 16.62 (6), 41.89 (5) and 71.27 (4)° with the Ph rings. In the crystal, weak C-H···O hydrogen bonds link the mols. into supramol. chains along the b axis. Crystallog. data are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H20ClN3, Synthetic Route of 4551-69-3.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Dehbi, Ouarda published the artcileBis(4-benzoyl-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-olato-κ²O,O’)(methanol-κO)dioxidouranium(VI) methanol monosolvate, Safety of 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is Acta Crystallographica, Section E: Structure Reports Online (2012), 68(4), m457-m458, database is CAplus and MEDLINE.

In the title compound, [U(C₁₇H₁₃N₂O₂)₂O₂(MeOH)]·MeOH, the U^VI ion is coordinated by seven O atoms in a distorted pentagonal-bipyramidal geometry with two 3-methyl-1-phenyl-4-benzoyl-4,5-dihydro-1H-pyrazol-5-olate groups with two O atoms in a bidentate chelating coordination mode and by three O atoms, one of which is from a MeOH ligand. The crystal packing can be described by alternating layers of complex mols. along the a axis. The structure is stabilized by O-H···N and O-H···O H bonding and van der Waals interactions. Crystallog. data and at. coordinates are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Safety of 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics