Category: 4551-69-3

Wang, An published the artcileStudy on ring-opening polymerization of ε-caprolactone catalyzed by Zn(II) Schiff-base complex, Application In Synthesis of 4551-69-3, the publication is Shandong Huagong (2018), 47(20), 5-7, database is CAplus.

Ring-opening polymerization of ε-caprolactone catalyzed by Zn(II) Schiff-base complex [LZn] was studied. Using the selected [LZn] as the catalyst and 4-dimethylaminopyridine as the co-catalyst from the polymerization temperature of 80°C and the reaction time of 6 h in the solvent of toluene, the ring-opening polymerization of ε-caprolactone was carried out under nitrogen atm., where the Mn of the PCL was 24.653×10³ g·mol^-1 and the PDI was 1.21. The results showed that the effective ring-opening polymerization of ε-caprolactone was realized with the presence of catalyst [LZn].

Shandong Huagong published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C9H17NO, Application In Synthesis of 4551-69-3.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhu, Hualing published the artcileStructures, spectroscopic analysis, herbicidal activities and enamine-aminone tautomerism of new β-diketone derivatives modified with glycylglycine methyl ester, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is Journal of Molecular Structure (2015), 170-177, database is CAplus.

New β-diketone derivatives modified with glycylglycine Me ester have been synthesized and characterized by IR, UV, ¹H NMR, ¹³C NMR, Elemental anal. and single-crystal X-ray diffraction, the anal. results show that compound 1 and compound 2a exist in enamine form while compound 2b exists in aminone form. The optimized geometries and theor. vibrational frequencies of the compounds calculated by using DFT/B3LYP with 6-31g (d, p) basis set in the ground state can well reproduce the exptl. data. The results of herbicidal activity tests indicate that all the tested compounds own higher inhibition ability to monocotyledon than to dicotyledon, especially to green-bristlegrass with the inhibitory rates about 100%. Theor. enamine-aminone tautomerism study at DFT/B3LYP/6-31g (d, p) shows that tautomerism between compound 2a and 2b is mainly caused by the proton transfer.

Journal of Molecular Structure published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C15H10O2, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhao, Bin published the artcileNovel mixed ligand di-n-butyltin(IV) complexes derived from acylpyrazolones and fluorinated benzoic acids: Synthesis, characterization, cytotoxicity and the induction of apoptosis in Hela cancer cells, Category: pyrazoles-derivatives, the publication is European Journal of Medicinal Chemistry (2014), 87-97, database is CAplus and MEDLINE.

Twenty one novel mixed ligand di-n-butyltin(IV) complexes [ⁿBu₂SnAL] (A = substituted 4-acyl-5-pyrazolone, and L = fluorinated benzoic acid) were prepared by condensation of di-n-butyltin(IV) oxide with HL and HA in 1:1:1 molar ratio in refluxing methanol. All of the complexes were characterized by elemental analyses, IR, NMR (¹H, ¹³C, ¹¹⁹Sn) and in four cases by X-ray diffraction. Cytotoxicity of the compounds was studied against two human cancer cell lines (KB and Hela) by means of the MTT assay compared to cisplatin, featuring IC₅₀ values in the low micromolar range. Hela cancer cell apoptosis-induced by 2 was examined by flow cytometry anal., and preliminary results showed that 2 at concentrations of more than 1.0 μM can induce apoptosis.

European Journal of Medicinal Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C12H23N3S, Category: pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Maurya, Mannar R. published the artcileVanadium(IV and V) complexes of pyrazolone based ligands: Synthesis, structural characterization and catalytic applications, Related Products of pyrazoles-derivatives, the publication is Dalton Transactions (2016), 45(43), 17343-17364, database is CAplus and MEDLINE.

The ONO donor ligands obtained from the condensation of 4-benzoyl-3-methyl-1-phenyl-2-pyrazoline-5-one (Hbp) with benzoylhydrazide (H₂bp-bhz I), furoylhydrazide (H₂bp-fah II), nicotinoylhydrazide (H₂bp-nah III) and isonicotinoylhydrazide (H₂bp-inh IV), upon treatment with [V^IVO(acac)₂], give [V^IVO(bp-bhz)(H₂O)] 1, [V^IVO(bp-fah)(H₂O)] 2, [V^IVO(bp-nah)(H₂O)] 3 and [V^IVO(bp-inh)(H₂O)] 4, resp. At neutral pH the in situ generated aqueous K[H₂V^VO₄] reacts with ligands I and II, forming potassium salts, K(H₂O)₂[V^VO₂(bp-bhz)] 5 and K(H₂O)₂[V^VO₂(bp-fah)] 6, while ligands III and IV give neutral complexes, [V^VO₂(Hbp-nah)] 9 and [V^VO₂(Hbp-inh)] 10, resp. Acidification of aqueous solutions of 5 and 6 with HCl also gives neutral complexes [V^VO₂(Hbp-bhz)] 7 and [V^VO₂(Hbp-fah)] 8, resp. Complexes 1–4, upon slow aerial oxidation in methanol, convert into monooxidovanadium(V) complexes, [V^VO(bp-bhz)(OMe)] 11, [V^VO(bp-fah)(OMe)] 12, [V^VO(bp-nah)(OMe)] 13 and [V^VO(bp-inh)(OMe)] 14, resp. All complexes were characterized by various spectroscopic techniques like FTIR, UV-visible, EPR (for complexes 1–4) and NMR (¹H, ¹³C and ⁵¹V), elemental anal., TG and single crystal x-ray diffraction (for complexes 5–10 and 12). In the solid state, all complexes characterized by x-ray diffraction show the metal ion 5-coordinated in a distorted square pyramidal geometry. Complexes 11–14 were tested as catalysts for the one-pot three-component (ethylacetoacetate, benzaldehyde and ammonium acetate) dynamic covalent assembly, via Hantzsch reaction, using hydrogen peroxide as oxidant in solution and under solvent-free conditions. The complexes are also active catalysts for the oxidation of tetralin to tetralone with H₂O₂ as oxidant. The influence of the amounts of catalyst and oxidant, and solvent, temperature and time on the catalyzed reactions was investigated.

Dalton Transactions published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Related Products of pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Sathiyaraj, Subbaiyan published the artcileSynthesis, Spectral Characterization, DNA Binding, DNA Cleavage, and Antioxidant Studies of Ruthenium(III) Heterocyclic Thiosemicarbazone Complexes, Application In Synthesis of 4551-69-3, the publication is Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry (2014), 44(9), 1261-1271, database is CAplus.

The reactions of benzothiazolyl thiosemicarbazone with [RuX₃(PPh₃)₃] (X = Cl/Br) in a 1:1 molar ratio gave stable solid complexes corresponding to [RuX(PPh₃)₂(L)]. Structural features were determined by anal. and spectral techniques. DNA binding properties of the ligands and its Ru(III) complexes were studied by electronic absorption spectroscopy. The complexes show good binding affinity to calf-thymus DNA. Gel electrophoresis of pBR322 DNA with complexes demonstrated that the complexes exhibit excellent cleavage activity via oxidative pathway. The antioxidant activity of the free ligands and its complexes was determined by DPPH and hydroxyl radicals. The complexes possess potent antioxidant activity.

Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Application In Synthesis of 4551-69-3.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Idemudia, Omoruyi G. published the artcile3-Methyl-1-phenyl-4-[(phenyl)(2-phenylhydrazin-1-yl)methylidene]-1H-pyrazol-5(4H)-one, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is Acta Crystallographica, Section E: Structure Reports Online (2012), 68(5), o1280-o1281, database is CAplus and MEDLINE.

The title compound, C₂₃H₂₀N₄O, is a heterocyclic phenylhydrazone Schiff base with a pyrazole moiety. In the crystal, a variety of interactions occur, including N-H···π and π-π stacking between the Ph ring of the phenylhydrazinyl group and its symmetry-generated equivalent [centroid-centroid distance = 3.6512(7) Å]. Crystallog. data and at. coordinates are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Idemudia, Omoruyi G. published the artcile4-{[2-(2,4-Dinitrophenyl)hydrazinylidene](phenyl)methyl}-5-methyl-2-phenyl-1H-pyrazol-3(2H)-one ethanol monosolvate, Safety of 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is Acta Crystallographica, Section E: Structure Reports Online (2012), 68(12), o3380, database is CAplus and MEDLINE.

In the title compound, C₂₃H₁₈N₆O₅·C₂H₆O, all three benzene rings lie in an approx. plane [maximum deviation = 0.2688(16) Å] that makes an angle of 53.56(3)° with the plane of the pyrazolone ring. Intramol. N-H···O H bonds occur. In the crystal, the EtOH solvent mol. links adjacent mols. through N-H···O-H···O H bonds, leading to an infinite chain along the c-axis direction. The Et group of the EtOH solvent mol. is disordered over two set of sites in a 0.762(5):0.238(5) ratio. Crystallog. data and at. coordinates are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Safety of 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Idemudia, Omoruyi G. published the artcileMetal complexes of new bioactive pyrazolone phenylhydrazones; crystal structure of 4-acetyl-3-methyl-1-phenyl-2-pyrazoline-5-one phenylhydrazone Ampp-Ph, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is International Journal of Molecular Sciences (2016), 17(5), 687/1-687/24, database is CAplus and MEDLINE.

The condensation reaction of phenylhydrazine and dinitrophenylhydrazine with 4-acetyl and 4-benzoyl pyrazolone precipitated air-stable acetyldinitrophenylhydrazone Ampp-Dh, benzoylphenylhydrazone Bmpp-Ph and benzoyldinitrophenylhydrazone Bmpp-Dh in their keto imine form; a study inspired by the burning interest for the development of new bioactive materials with novel properties that may become alternative therapeutic agents. Elemental anal., FTIR, 1H, and 13C NMR, and mass spectroscopy have been used to justify their proposed chem. structures, which were in agreement with the single crystal structure of Bmpp-Dh earlier reported according to X-ray crystallog. The single crystal structure of 4-acetyl-3-methyl-1-phenyl-pyrazoline-5-one phenylhydrazone Ampp-Ph, which crystallizes in a triclinic crystal system with a P-1 (Number 2) space group is presented. Octahedral Mn(II), Ni(II), Co(II), and Cu(II) complexes of these resp. ligands with two mols. each of the bidentate Schiff base, coordinating to the metal ion through the azomethine nitrogen C=N and the keto oxygen C=O, which were afforded by the reaction of aqueous solutions of the corresponding metal salts with the ligands are also reported. Their identity and proposed structures were according to elemental anal., FTIR spectroscopy, UV-VIS spectrophotometry (electronic spectra) and Bohr magnetic moments, as well as thermogravimetric anal. (TGA) results. A look at the antibacterial and antioxidant activities of synthesized compounds using the methods of the disk diffusion against some selected bacterial isolates and 1,1-diphenyl-2-picryl-hydrazil (DPPH) resp., showed biol. activities in relation to employed standard medicinal drugs.

International Journal of Molecular Sciences published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhou, Fang-qin published the artcileOn-line separation and preconcentration of trace cadmium in environmental water samples by micro column filled with modified nanometer Si-HAP prior to FAAS determination, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is International Journal of Environmental Analytical Chemistry (2012), 92(7), 821-831, database is CAplus.

A method of online solid phase extraction (SPE) preconcentration was established for the determination of Cd in environmental water samples by flame at. absorption spectrometry (FAAS). The method is based on the online retention of Cd on a microcolumn of nanometer silicon hydroxyapatite (Si-HAP) modified with 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone (PMBP) and subsequent elution with 1.0 M thiourea and determination by FAAS. The effect of various parameters that could affect the performance of the system was investigated. The enrichment factor (EF) for Cd was 250. The limit of detection (LOD) obtained under optimum conditions was 0.28 μg/L^-1 and the RSD for ₇ replicates at 100 μg/L^-1 Cd²⁺ concentration level was 1.4%. The method was applied to water samples and standard reference materials. The accuracy was assessed through recovery experiments and comparing the results with the accepted values of standard reference material.

International Journal of Environmental Analytical Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C6H13BO3, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Idemudia, Omoruyi G. published the artcileSynthesis and characterization of bioactive acylpyrazolone sulfanilamides and their transition metal complexes: single crystal structure of 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one sulfanilamide, COA of Formula: C17H14N2O2, the publication is Bioinorganic Chemistry and Applications (2015), 1-15, database is CAplus and MEDLINE.

Two Schiff base ligands Ampp-Sn (1) and Bmpp-Sn (2), afforded by a condensation reaction between sulfanilamide and the resp. acylpyrazolone carbonyl precursors, their Mn(II), Co(II), Ni(II), and Cu(II) complexes prepared by the reaction of ligands and corresponding metal salts in aqueous solutions, were synthesized and then characterized by both anal. and spectroscopic methods, in a view to developing new improved bioactive materials with novel properties. From elemental anal., spectroscopic and TGA results, transition metal complexes, with octahedral geometry having two mols. of the bidentate keto-imine ligand each, are proposed. The single crystal structure of Bmpp-Sn according to x-ray crystallog. showed a keto-imine tautomer type of Schiff base, having three intramol. bonds, one short N2···H2···O3 hydrogen bond of 1.90 Å and two long C13···H13···O2 and C32···H32···O3 hydrogen bonds of 2.48 Å. A moderate to low biol. activities were exhibited by synthesized compounds when compared with standard antimicrobial agents on screening the synthesized compounds against Staphylococcus aureus, Bacillus pumilus, Proteus vulgaris, and Aeromonas hydrophila for antibacterial activity and against free radical 1,1-diphenyl-2-picryl-hydrazyl (DPPH) for antioxidant activity.

Bioinorganic Chemistry and Applications published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, COA of Formula: C17H14N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics