Category: 57446-04-5

On August 12, 1975, Wikel, James H. published a patent.COA of Formula: C11H9N3O4 The title of the patent was 5-(2-Aminophenyl)pyrazole-3-carboxylic acids and esters. And the patent contained the following:

MeO2CCO2Me was treated with MeCOC6H4NO2-2 and the o-O2NC6H4COCH2COCO2Et cyclized with H2NNH2 to give I (R = NO2), which was reduced to I (R = NH2). At 1-200 mg/kg I (R = NH2) was a complement inhibitor. The experimental process involved the reaction of Methyl 3-(2-nitrophenyl)-1H-pyrazole-5-carboxylate(cas: 57446-04-5).COA of Formula: C11H9N3O4

The Article related to complement inhibitor aminophenylpyrazolecarboxylate, pyrazolecarboxylate aminophenyl complement inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.COA of Formula: C11H9N3O4

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Vlasenko, Yulia A.; Kuczmera, Thomas J.; Antonkin, Nikita S.; Postnikov, Pavel S.; Nachtsheim, Boris J. published an article in 2022, the title of the article was Site selective nucleophilic aromatic substitutions of azole-ligated diaryliodonium salts.SDS of cas: 57446-04-5 And the article contains the following content:

Herein the application of azole-stabilized diaryliodonium salts with addnl. thiophen-2-yl-ligands as substrates for metal-free nucleophilic arylations was presented. Besides their synthesis, their application in chemoselective nitrations, oxygenations, aminations as well as thiolations under umpolung conditions was demonstrated. Convenient one-pot procedures that are based on their in situ formation are also discussed. The experimental process involved the reaction of Methyl 3-(2-nitrophenyl)-1H-pyrazole-5-carboxylate(cas: 57446-04-5).SDS of cas: 57446-04-5

The Article related to diaryliodonium triflate regioselective nucleophilic aromatic nitration reaction, nitro biaryle preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.SDS of cas: 57446-04-5

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics