Category: 25956-17-6

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate, is researched, Molecular C18H14N2Na2O8S2, CAS is 25956-17-6, about Unified chromatography – Mass spectrometry as a versatile tool for determination of food dyes, the main research direction is unified chromatog mass spectrometry food dye; Nonpolar dyes; Subsidiary colors; Sulfonated dyes; Supercritical fluid chromatography.SDS of cas: 25956-17-6.

Unified chromatog. with mass spectrometric detection was assessed for determination of food dyes. Nineteen substances representing azo, triphenylmethane, xanthone, indigoid, quinoline and polyene classes covering an unprecedented range from nonpolar β-Carotene (logD 13.6) to ionic Tartrazine (logD -7.5) were analyzed simultaneously. The dyes were separated in a single exptl. run by an 18-min gradient elution from 98% CO2 to 100% aqueous-methanolic modifier on a diol column. Isomeric substances were resolved, and Isatin Sulfonic acid was detected as a degradation product of Indigo Carmine. Mobile phase properties reproducibly changed from supercritical to liquid state ensuring stable retention times (inter-day RSD<0.5%). Quant. anal. of sports drinks after straightforward 10- or 25-fold dilution with DMSO confirmed the method applicability to real-life samples. Sufficient limits of detection (typically 0.025 mg L-1 in processed samples, equivalent to 0.25 mg L-1 in drink) and a wide linear range (typically 0.5-50 mg L-1 or 1.3-125 mg L-1 in drink for 10x or 25x dilution, resp.) were demonstrated during validation. A comparison of method performance with competitive liquid chromatog. procedures is also provided. Unified chromatog. is a promising tool for comprehensive multiclass anal. of dyes in the context of food safety. There is still a lot of research devoted to this compound(SMILES：O=S(C1=CC=C2C(/N=N/C3=CC(C)=C(S(=O)([O-])=O)C=C3OC)=C(O)C=CC2=C1)([O-])=O.[Na+].[Na+])SDS of cas: 25956-17-6, and with the development of science, more effects of this compound(25956-17-6) can be discovered.

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The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate( cas:25956-17-6 ) is researched.Computed Properties of C18H14N2Na2O8S2.Hua, Dengke; Zheng, Xiaobin; Zhang, Kun; Zhang, Zhen; Wan, Yanran; Zhou, Xuguo; Zhang, Youjun; Wu, Qingjun published the article 《Assessing Pesticide Residue and Spray Deposition in Greenhouse Eggplant Canopies to Improve Residue Analysis》 about this compound( cas:25956-17-6 ) in Journal of Agricultural and Food Chemistry. Keywords: spray deposition pesticide residue greenhouse eggplant canopy leaf; abamectin; manual air-pressure knapsack sprayer; pesticide residue; pesticide spray pattern. Let’s learn more about this compound (cas:25956-17-6).

Pesticide residue anal. is critically important for ensuring food safety and regulating international trade. In a greenhouse setting, we assessed pesticide residue and exposure patterns using liquid chromatog.-mass spectrometry and Allura Red tracer anal. Our results show significant effects of eggplant canopy position and spray concentration on deposition parameters. Specifically, spray coverage, spray d., deposition, and residue were generally greater for leaves in the higher canopy. Deposition and residue, unlike spray coverage and spray d., linearly correlated with spray concentration Pesticide residues on leaves linearly correlated with depositions on artificial targets, and a correction factor was constructed to estimate residues from tracer depositions. This comparative anal. suggests that tracer anal. using Allura Red in combination with artificial targets is a time- and cost-saving alternative to conventional residue anal. for assessing spray parameters under high-volume spraying scenarios. A better understanding of pesticide residue and spray patterns will not only enhance the safety of our food supply chain but also improve pest control efficacy within the sustainable integrated pest management framework.

There is still a lot of research devoted to this compound(SMILES：O=S(C1=CC=C2C(/N=N/C3=CC(C)=C(S(=O)([O-])=O)C=C3OC)=C(O)C=CC2=C1)([O-])=O.[Na+].[Na+])Computed Properties of C18H14N2Na2O8S2, and with the development of science, more effects of this compound(25956-17-6) can be discovered.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate(SMILESS: O=S(C1=CC=C2C(/N=N/C3=CC(C)=C(S(=O)([O-])=O)C=C3OC)=C(O)C=CC2=C1)([O-])=O.[Na+].[Na+],cas:25956-17-6) is researched.Application In Synthesis of 1-(4-Chlorophenyl)pyrrolidin-2-one. The article 《Exploring Chemical Kinetics at Home in Times of Pandemic: Following the Bleaching of Food Dye Allura Red Using a Smartphone》 in relation to this compound, is published in Journal of Chemical Education. Let’s take a look at the latest research on this compound (cas:25956-17-6).

In this communication, a remote exptl. activity in chem. kinetics is described, taking into account the quantification based on the optical sensor of a smartphone. The objective pursued herein is to equip students with the appropriate tools and strategies required to empirically determine the parameters of the rate law including reaction orders, rate constant (k), frequency factor (A), and activation energy (Ea). Typical results of the proposed protocol are shown and discussed in the framework of the bleaching reaction of food dye allura red (RD40) and hypochlorite, as a representative example. A graphical approach of the concentration vs time data measured under the exptl. condition where [RD40] ≪ [ClO-] (isolation method) suggests a first-order kinetics with respect to the dye. In addition, the anal. of the pseudo-first-order constant (kobs) shows a first-order relationship with respect to ClO-. In addition, using the two-point form of the Arrhenius equation, values of 3.22 x 107 s/M and 44.55 kJ/mol were obtained for A and Ea, resp. Interestingly, all the kinetic parameters (reaction orders, k, A, and Ea) are on the same order of magnitude as those previously reported in the literature and acquired with more sophisticated and accurate equipment. This experience provides evidence that it is possible to proceed with remote exptl. activities to deepen the collection and anal. of kinetic data during a pandemic.

If you want to learn more about this compound(Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate)Application of 25956-17-6, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(25956-17-6).

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Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Journal of Food Processing and Preservation called Ingredient photostability as affected by iron: Colorant degradation, Author is James, Cierra A.; Bell, Leonard N., which mentions a compound: 25956-17-6, SMILESS is O=S(C1=CC=C2C(/N=N/C3=CC(C)=C(S(=O)([O-])=O)C=C3OC)=C(O)C=CC2=C1)([O-])=O.[Na+].[Na+], Molecular C18H14N2Na2O8S2, Product Details of 25956-17-6.

Understanding factors that affect food chem. stability is important for optimizing product quality and shelf life. The objective of this project was to investigate the role of iron and UV light on chem. stability by determining the degradation rate constants of Brilliant Blue, tartrazine, and Allura Red in pH 3 solutions of various compositions stored in the presence and absence of UV light. The storage of solutions in darkness at 30°C resulted in no observable loss of any colorant. Exposure to UV light significantly (p < .05) increased the degradation rate constants Colorant degradation was fastest in the presence of citrate, iron, and UV light. Iron-citrate complexes are likely forming hydroxyl radicals upon UV exposure, which enhance colorant degradation Photodegradation of food ingredients increases in the presence of iron and citrate buffer, resulting in a loss of shelf life. If you want to learn more about this compound(Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate)Product Details of 25956-17-6, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(25956-17-6).

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Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

HPLC of Formula: 25956-17-6. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate, is researched, Molecular C18H14N2Na2O8S2, CAS is 25956-17-6, about Solar Light Induced Glass-Supported Zinc Oxide Catalyzed Degradation of Allura Red AC in Aqueous Solution.

The glass-supported zinc oxide (ZnO)-catalyzed photodegradation of Allura Red AC (AR) was studied in aqueous solution as function of solar light irradiation time, solution pH, amount of ZnO, initial dye concentration, some inorganic anions (SO42-, CO32-, NO3-, Cl-), and hydrogen peroxide. The maximum rate of AR degradation was observed in the acidic solution at pH 3. The degradation rate of AR increased with increased dosage of the ZnO, and decreased with increased initial concentration of the dye solution The presence of [Formula Omitted] ion increased the photodegradation rate while,SO42-, CO32-, and Cl- decreased the reaction rate. The addition of H2O2 showed a synergistic effect on dye degradation However, mannitol and EDTA (EDTA) significantly reduced the photodegradation of AR indicating hydroxyl radicals played a key role in dye degradation process. Hence, these results confirm that the glass-supported ZnO-catalyzed photodegradation can be used to clean dye-contaminated industrial wastewater.

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Wartell, Brian A.; Boufadel, Michel C.; Rodriguez-Freire, Lucia; Axe, Lisa; Abrams, Stewart; Ciblak, Ali published an article about the compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate( cas:25956-17-6,SMILESS:O=S(C1=CC=C2C(/N=N/C3=CC(C)=C(S(=O)([O-])=O)C=C3OC)=C(O)C=CC2=C1)([O-])=O.[Na+].[Na+] ).Application of 25956-17-6. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:25956-17-6) through the article.

Self-designed electrokinetic setups were constructed to examine the differences in electromigration and electroosmotic rates in both sand and clay. Two dyes were analyzed sep. to measure these phenomena within these two media types. The dyes used were a red food coloring (primary compound Allura Red) and a green food coloring (referred to as a “”blue dye”” as its migrating component was C-phycocyanin (C-PC) via Spirulina Blue extract). The power supply had a 30 V output with a measured 9.36 ± 0.04 mA current (0.054 mA/cm2) output. Electromigration was readily apparent for the red dye in both sand (9.12 ± 1.57 cm/d) and clay (0.93 ± 0.16) cm/d. It was also observed for the blue dye (C-PC) in sand (7.28 ± 0.57 cm/d) but not in clay. A confirmation experiment for the blue dye in sand was performed at an identical voltage but a slightly lower current output (0.040 mA/cm2), and the migration rate was found to be similar, at 6.60 ± 0.20 cm/d. For the blue dye in clay, the migration rate proceeded toward the cathode at 0.17 cm/d. Calculations indicate this phenomenon to be due to electroosmosis but may be due to a weak electromigration of the dye in protonated form.

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The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Systematic assessment of mechanistic data for FDA-certified food colors and neurodevelopmental processes》. Authors are Chappell, G. A.; Britt, J. K.; Borghoff, S. J..The article about the compound:Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonatecas:25956-17-6,SMILESS:O=S(C1=CC=C2C(/N=N/C3=CC(C)=C(S(=O)([O-])=O)C=C3OC)=C(O)C=CC2=C1)([O-])=O.[Na+].[Na+]).Product Details of 25956-17-6. Through the article, more information about this compound (cas:25956-17-6) is conveyed.

Seven US FDA-batch certified synthetic food colors are approved for use as food additives in the United States. Perceived neurodevelopmental concerns for these colors persist. This study assessed the plausibility of such an association through the evaluation of mechanistic evidence collected from in vitro assays or other alternative models. Mechanisms and mol. targets underlying neurodevelopmental processes associated with attention deficit and hyperactivity disorder (ADHD) and other neurodevelopmental-related symptoms (e.g., cognitive function, learning and memory disorder, etc.) were identified. Publicly available data from the ToxCast/Tox21 high-throughput screening (HTS) program and peer-reviewed literature that measure activity of the colors for such mol. targets were analyzed and reviewed. Erythrosine (Red Number 3) was active in several assays mapped to neurodevelopmental processes – specifically, HTS assays that measure signals in neurotransmitter pathways. The remaining six colors do not appear to alter signaling pathways related to neurodevelopmental processes on the mol. or cellular level. This assessment provides an approach for systematically identifying and mapping mechanistic data to putative neurodevelopmental processes as a means to prioritize substances for possible further investigation. The assessment also provides insights into the lack of activity of synthetic food colors for key events in neurodevelopmental signaling pathways.

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Formula: C18H14N2Na2O8S2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate, is researched, Molecular C18H14N2Na2O8S2, CAS is 25956-17-6, about Food Additives as Inhibitors of Intestinal Drug Transporter OATP2B1. Author is Tikkanen, Alli; Pierrot, Estelle; Deng, Feng; Sanchez, Virginia Barras; Hagstrom, Marja; Koenderink, Jan B.; Kidron, Heidi.

Food additives are compounds that are added to food and beverage to improve the taste, color, preservation, or composition Generally, food additives are considered safe for human use due to safety evaluations conducted by food safety authorities and high safety margins applied to permitted usage levels. However, the interaction potential of food additives with simultaneously administered medication has not received much attention. Even though many food additives are poorly absorbed into systemic circulation, high concentrations could exist in the intestinal lumen, making intestinal drug transporters, such as the uptake transporter organic anion transporting polypeptide 2B1 (OATP2B1), a possible site of food additive-drug interactions. In the present work, we aimed to characterize the interaction of a selection of 25 food additives including colorants, preservatives, and sweeteners with OATP2B1 in vitro. In human embryonic kidney 293 (HEK293) cells transiently overexpressing OATP2B1 or control, uptake of dibromofluorescein was studied with and without 50μM food additive at pH 7.4. As OATP2B1 displays substrate- and pH-dependent transport functions and the intraluminal pH varies along the gastrointestinal tract, we performed the studies also at pH 5.5 using estrone sulfate as an OATP2B1 substrate. Food additives that inhibited OATP2B1-mediated substrate transport by ≥50% were subjected to dose-response studies. Six colorants were identified and validated as OATP2B1 inhibitors at pH 5.5, but only three of these were categorized as inhibitors at pH 7.4. One sweetener was validated as an inhibitor under both assay conditions, whereas none of the preservatives exhibited ≥50% inhibition of OATP2B1-mediated transport. Extrapolation of computed inhibitory constants (Ki values) to estimations of intestinal food additive concentrations implies that selected colorants could inhibit intestinal OATP2B1 also in vivo. These results suggest that food additives, especially colorants, could alter the pharmacokinetics of orally administered OATP2B1 substrate drugs, although further in vivo studies are warranted to understand the overall clin. consequences of the findings.

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