Category: 59843-75-3

Some common heterocyclic compound, 59843-75-3, name is 3-(p-Tolyl)-1H-pyrazole, molecular formula is C10H10N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Product Details of 59843-75-3

Production Example 143 3-p-Tolyl-1-trityl-1H-pyrazole 6.94 g of the title compound was obtained as pale brown crystals from 4.59 g 3-p-tolyl-1H-pyrazole (compound in Production Example 126) by the same method as in Production Example 15.1H-NMR (CDCl3) delta: 2.35(s, 3H), 6.50(d, J=2.4Hz, 1H), 7.16(d, J=8.0Hz, 2H), 7.21(m, 6H), 7.27 (d, J=2. 4Hz, 1H), 7.30(m, 9H), 7.69(d, J=8.0Hz, 2H)

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 59843-75-3, its application will become more common.

Reference:
Patent; Eisai Co., Ltd.; EP1382603; (2004); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 59843-75-3, name is 3-(p-Tolyl)-1H-pyrazole, A new synthetic method of this compound is introduced below., Recommanded Product: 59843-75-3

EXAMPLE 24 N,N,alpha-Trimethyl-3-(p-tolyl)pyrazole-1-acetamide Following the procedure of Example 1, but substituting 3-(p-tolyl)pyrazole for 4-methyl-3-phenylpyrazole there was obtained N,N,alpha-trimethyl-3-(p-tolyl)pyrazole-1-acetamide having a melting point of 79-82 C. Analysis: Calc’d. for C15 H19 N3 O: C, 70.00; H, 7.44; N, 16.33. Found: C, 70.24; H, 7.29; N, 16.60.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; The Upjohn Company; US4072498; (1978); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics