Category: 52096-24-9

Product Details of 52096-24-9On March 17, 2017, Kim, Og Soon; Jang, Jin Hyeok; Kim, Hyun Tae; Han, Su Jin; Tsui, Gavin Chit; Joo, Jung Min published an article in Organic Letters. The article was 《Synthesis of Fluorescent Indazoles by Palladium-Catalyzed Benzannulation of Pyrazoles with Alkynes》. The article mentions the following:

Pentasubstituted indazoles such as I (R = H, Me, t-Bu, MeO, EtO2C, F, Cl) were prepared in 34-84% yields by oxidative benzannulation reactions of pyrazoles such as 1-methylpyrazole with sym. internal alkynes such as 4-(4-RC6H4CC)C6H4R (R = H, Me, t-Bu, MeO, EtO2C, F, Cl) in the presence of Pd(OAc)2 and Cu(OAc)2 in 1,4-dioxane or by benzannulation of substituted 4-bromopyrazoles with sym. internal alkynes in the presence of Pd(OAc)2, t-Bu3P•HBF4, K2CO3, and pivalic acid in toluene; unsym. internal alkynes gave mixtures of regioisomers. 1,2-Disubstituted imidazoles also underwent oxidative benzannulation with diphenylacetylene in the presence of Pd(OAc)2 and Cu(OAc)2 in 1,4-dioxane to yield tetraphenylbenzimidazoles in 41-50% yields. The fluorescence and optical bandgaps of I (R = H, t-Bu, MeO, EtO2C, F, Cl) were determined The structure of I (R = H) was determined by X-ray crystallog. In the part of experimental materials, we found many familiar compounds, such as 1-Butyl-1H-pyrazole(cas: 52096-24-9Product Details of 52096-24-9)

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Product Details of 52096-24-9

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

The author of 《Infrared spectra of pyrazoles. I. Monoalkyl-substituted pyrazoles》 were Zerbi, Giuseppe; Alberti, Carlo. And the article was published in Spectrochimica Acta in 1962. Recommanded Product: 52096-24-9 The author mentioned the following in the article:

The compounds studied were pyrazole, 3-alkyl-, 4-alkyl-, and N-alkylpyrazole, where the substituents were Me, Et, Pr, Bu, and amyl. The spectral region was 2-15 μ. Observed bands can be used to recognize the pyrazole structure and the position of the substituent. Most of the observed bands were assigned. In addition to this study using 1-Butyl-1H-pyrazole, there are many other studies that have used 1-Butyl-1H-pyrazole(cas: 52096-24-9Recommanded Product: 52096-24-9) was used in this study.

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Recommanded Product: 52096-24-9

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Related Products of 52096-24-9On March 31, 2013, Fokin, S. V.; Kostina, E. T.; Tret’yakov, E. V.; Romanenko, G. V.; Bogomyakov, A. S.; Sagdeev, R. Z.; Ovcharenko, V. I. published an article in Russian Chemical Bulletin. The article was 《Spin transition in the molecular heterospin complex of Cu(hfac)2 with 4,4,5,5-tetramethyl-2-(1-methylpyrazol-5-yl)-4,5-dihydroimidazole-1-oxyl 3-oxide》. The article mentions the following:

The synthesis, structure, and magnetic properties of the products of the reaction for Cu(hfac)2 (hfac is hexafluoroacetylacetonate) with spin-labeled nitronyl nitroxides 4,4,5,5-tetramethyl-2-(1-R-1H-pyrazol-5-yl)-3-imidazoline-1-oxyl 3-oxides L5/R (R = Me, Et, Pr, Bu), viz., binuclear complex [Cu(hfac)2L5/Me]2 and chain polymer complexes [Cu(hfac)2L5/R]n, are described. The polymer heterospin chains are built according to head-to-head (R = Me, Et, Pr, Bu) and head-to-tail (R = Pr, Bu) motifs. [Cu(hfac)2L5/Me]2 was characterized by the ability to reveal the reversible effect of thermally induced spin transition at a temperature ∼75 K (without hysteresis). In the set of heterospin CuII compounds with spin-labeled pyrazoles, this is the earlier unknown example of a mol. complex exhibiting a similar magnetic anomaly. In addition to this study using 1-Butyl-1H-pyrazole, there are many other studies that have used 1-Butyl-1H-pyrazole(cas: 52096-24-9Related Products of 52096-24-9) was used in this study.

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Related Products of 52096-24-9

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Ovcharenko, Victor; Fursova, Elena; Romanenko, Galina; Eremenko, Igor; Tretyakov, Evgeny; Ikorskii, Vladimir published an article in Inorganic Chemistry. The title of the article was 《Synthesis, Structure, and Magnetic Properties of (6-9)-Nuclear Ni(II) Trimethylacetates and Their Heterospin Complexes with Nitroxides》.Safety of 1-Butyl-1H-pyrazole The author mentioned the following in the article:

New polynuclear nickel trimethylacetates [Ni6(OH)4(C5H9O2)8(C5H10O2)4] (6), [Ni7(OH)7(C5H9O2)7(C5H10O2)6(H2O)]·0.5C6H14·0.5H2O (7), [Ni8(OH)4(H2O)2(C5H9O2)12] (8), and [Ni9(OH)6(C5H9O2)12(C5H10O2)4]·C5H10O2·3H2O (9), where C5H9O2 is trimethylacetate and C5H10O2 is trimethylacetic acid, were found. Their structures were determined by x-ray crystallog. Because of their high solubility in low-polarity organic solvents, compounds 6-9 reacted with stable organic radicals to form the first heterospin compounds based on polynuclear Ni(II) trimethylacetate and nitronyl nitroxides containing pyrazole (L1-L3), Me (L4), or imidazole (L5) substituent groups, resp., in side chains [Ni7(OH)5(C5H9O2)9(C5H10O2)2(L1)2(H2O)]·0.5C6H14·H2O (6+1a), [Ni7(OH)5(C5H9O2)9(C5H10O2)2(L2)2(H2O)]·H2O (6+1b), [Ni7(OH)5(C5H9O2)9(C5H10O2)2(L3)2(H2O)]·H2O (6+1c), [Ni6(OH)3(C5H9O2)9(C5H10O2)4(L4)]·1.5C6H14 (6”), and [Ni4(OH)3(C5H9O2)5(C5H10O2)4(L5)]·1.5C7H8 (4). Their structures were also determined by x-ray crystallog. Although Ni(II) trimethylacetates may have varying nuclearity and can change their nuclearity during recrystallization or interactions with nitroxides, this family of compounds is easy to study because of its topol. relation. For any of these complexes, the polynuclear framework may be derived from the [Ni6] polynuclear fragment {Ni6(μ4-OH)2(μ3-OH)2(μ2-C5H9O2-O,O’)6(μ2-C5H9O2-O,O)(μ4-C5H9O2-O,O,O’,O’)(C5H10O2)4}, which is shaped like an open book. From this fragment, the structure of 7-nuclear compounds (7 and 6+1a-c) is conveniently represented as the result of sym. addition of other mononuclear fragments to the four Ni(II) ions lying at the vertexes of the [Ni6] open book. The 9-nuclear complex is formed by the addition of trinuclear fragments to two Ni(II) ions lying on one of the lateral edges of the [Ni6] open book. This wing of the 9-nuclear complex preserves its structure in another type of 6-nuclear complex (6”) with the boat configuration. If, however, two edge-sharing Ni(II) ions are removed from [Ni6] (one of these lies at a vertex of the open book and the other, on the book-cover line), one obtains a 4-nuclear fragment recorded in the mol. structure of 4. Twinning of this 4-nuclear fragment forms highly sym. mol. 8, which is a new chem. version of cubane. In the part of experimental materials, we found many familiar compounds, such as 1-Butyl-1H-pyrazole(cas: 52096-24-9Safety of 1-Butyl-1H-pyrazole)

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Safety of 1-Butyl-1H-pyrazole

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Safety of 1-Butyl-1H-pyrazoleOn September 30, 1990 ,《Synthesis of N-alkylpyrazoles by phase transfer catalysis without solvent》 was published in Synthetic Communications. The article was written by Diez-Barra, E.; De la Hoz, A.; Sanchez-Migallon, A.; Tejeda, J.. The article contains the following contents:

The reaction of alkyl halides with pyrazoles in the presence of Bu4N+ Br- without solvent gave 36-98% N-alkylpyrazoles I [R = Me(CH2)n, PhCH2, CH2:CHCH2, CH2:C:CH; n = 0, 1, 3, 7, 15].1-Butyl-1H-pyrazole(cas: 52096-24-9Safety of 1-Butyl-1H-pyrazole) was used in this study.

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Safety of 1-Butyl-1H-pyrazole

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

The author of 《Infrared spectra of pyrazoles. I. Monoalkyl-substituted pyrazoles》 were Zerbi, Giuseppe; Alberti, Carlo. And the article was published in Spectrochimica Acta in 1962. Recommanded Product: 52096-24-9 The author mentioned the following in the article:

The compounds studied were pyrazole, 3-alkyl-, 4-alkyl-, and N-alkylpyrazole, where the substituents were Me, Et, Pr, Bu, and amyl. The spectral region was 2-15 μ. Observed bands can be used to recognize the pyrazole structure and the position of the substituent. Most of the observed bands were assigned. In addition to this study using 1-Butyl-1H-pyrazole, there are many other studies that have used 1-Butyl-1H-pyrazole(cas: 52096-24-9Recommanded Product: 52096-24-9) was used in this study.

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Recommanded Product: 52096-24-9

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Related Products of 52096-24-9On March 31, 2013, Fokin, S. V.; Kostina, E. T.; Tret’yakov, E. V.; Romanenko, G. V.; Bogomyakov, A. S.; Sagdeev, R. Z.; Ovcharenko, V. I. published an article in Russian Chemical Bulletin. The article was 《Spin transition in the molecular heterospin complex of Cu(hfac)2 with 4,4,5,5-tetramethyl-2-(1-methylpyrazol-5-yl)-4,5-dihydroimidazole-1-oxyl 3-oxide》. The article mentions the following:

The synthesis, structure, and magnetic properties of the products of the reaction for Cu(hfac)2 (hfac is hexafluoroacetylacetonate) with spin-labeled nitronyl nitroxides 4,4,5,5-tetramethyl-2-(1-R-1H-pyrazol-5-yl)-3-imidazoline-1-oxyl 3-oxides L5/R (R = Me, Et, Pr, Bu), viz., binuclear complex [Cu(hfac)2L5/Me]2 and chain polymer complexes [Cu(hfac)2L5/R]n, are described. The polymer heterospin chains are built according to head-to-head (R = Me, Et, Pr, Bu) and head-to-tail (R = Pr, Bu) motifs. [Cu(hfac)2L5/Me]2 was characterized by the ability to reveal the reversible effect of thermally induced spin transition at a temperature ∼75 K (without hysteresis). In the set of heterospin CuII compounds with spin-labeled pyrazoles, this is the earlier unknown example of a mol. complex exhibiting a similar magnetic anomaly. In addition to this study using 1-Butyl-1H-pyrazole, there are many other studies that have used 1-Butyl-1H-pyrazole(cas: 52096-24-9Related Products of 52096-24-9) was used in this study.

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Related Products of 52096-24-9

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Ovcharenko, Victor; Fursova, Elena; Romanenko, Galina; Eremenko, Igor; Tretyakov, Evgeny; Ikorskii, Vladimir published an article in Inorganic Chemistry. The title of the article was 《Synthesis, Structure, and Magnetic Properties of (6-9)-Nuclear Ni(II) Trimethylacetates and Their Heterospin Complexes with Nitroxides》.Safety of 1-Butyl-1H-pyrazole The author mentioned the following in the article:

New polynuclear nickel trimethylacetates [Ni6(OH)4(C5H9O2)8(C5H10O2)4] (6), [Ni7(OH)7(C5H9O2)7(C5H10O2)6(H2O)]·0.5C6H14·0.5H2O (7), [Ni8(OH)4(H2O)2(C5H9O2)12] (8), and [Ni9(OH)6(C5H9O2)12(C5H10O2)4]·C5H10O2·3H2O (9), where C5H9O2 is trimethylacetate and C5H10O2 is trimethylacetic acid, were found. Their structures were determined by x-ray crystallog. Because of their high solubility in low-polarity organic solvents, compounds 6-9 reacted with stable organic radicals to form the first heterospin compounds based on polynuclear Ni(II) trimethylacetate and nitronyl nitroxides containing pyrazole (L1-L3), Me (L4), or imidazole (L5) substituent groups, resp., in side chains [Ni7(OH)5(C5H9O2)9(C5H10O2)2(L1)2(H2O)]·0.5C6H14·H2O (6+1a), [Ni7(OH)5(C5H9O2)9(C5H10O2)2(L2)2(H2O)]·H2O (6+1b), [Ni7(OH)5(C5H9O2)9(C5H10O2)2(L3)2(H2O)]·H2O (6+1c), [Ni6(OH)3(C5H9O2)9(C5H10O2)4(L4)]·1.5C6H14 (6”), and [Ni4(OH)3(C5H9O2)5(C5H10O2)4(L5)]·1.5C7H8 (4). Their structures were also determined by x-ray crystallog. Although Ni(II) trimethylacetates may have varying nuclearity and can change their nuclearity during recrystallization or interactions with nitroxides, this family of compounds is easy to study because of its topol. relation. For any of these complexes, the polynuclear framework may be derived from the [Ni6] polynuclear fragment {Ni6(μ4-OH)2(μ3-OH)2(μ2-C5H9O2-O,O’)6(μ2-C5H9O2-O,O)(μ4-C5H9O2-O,O,O’,O’)(C5H10O2)4}, which is shaped like an open book. From this fragment, the structure of 7-nuclear compounds (7 and 6+1a-c) is conveniently represented as the result of sym. addition of other mononuclear fragments to the four Ni(II) ions lying at the vertexes of the [Ni6] open book. The 9-nuclear complex is formed by the addition of trinuclear fragments to two Ni(II) ions lying on one of the lateral edges of the [Ni6] open book. This wing of the 9-nuclear complex preserves its structure in another type of 6-nuclear complex (6”) with the boat configuration. If, however, two edge-sharing Ni(II) ions are removed from [Ni6] (one of these lies at a vertex of the open book and the other, on the book-cover line), one obtains a 4-nuclear fragment recorded in the mol. structure of 4. Twinning of this 4-nuclear fragment forms highly sym. mol. 8, which is a new chem. version of cubane. In the part of experimental materials, we found many familiar compounds, such as 1-Butyl-1H-pyrazole(cas: 52096-24-9Safety of 1-Butyl-1H-pyrazole)

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Safety of 1-Butyl-1H-pyrazole

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Safety of 1-Butyl-1H-pyrazoleOn September 30, 1990 ,《Synthesis of N-alkylpyrazoles by phase transfer catalysis without solvent》 was published in Synthetic Communications. The article was written by Diez-Barra, E.; De la Hoz, A.; Sanchez-Migallon, A.; Tejeda, J.. The article contains the following contents:

The reaction of alkyl halides with pyrazoles in the presence of Bu4N+ Br- without solvent gave 36-98% N-alkylpyrazoles I [R = Me(CH2)n, PhCH2, CH2:CHCH2, CH2:C:CH; n = 0, 1, 3, 7, 15].1-Butyl-1H-pyrazole(cas: 52096-24-9Safety of 1-Butyl-1H-pyrazole) was used in this study.

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Safety of 1-Butyl-1H-pyrazole

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Application In Synthesis of 1-Butyl-1H-pyrazoleOn November 30, 2014 ,《Proton Transfer Reaction Time-of-Flight Mass Spectrometric (PTR-TOF-MS) determination of volatile organic compounds (VOCs) emitted from a biomass fire developed under stable nocturnal conditions》 appeared in Atmospheric Environment. The author of the article were Brilli, Federico; Gioli, Beniamino; Ciccioli, Paolo; Zona, Donatella; Loreto, Francesco; Janssens, Ivan A.; Ceulemans, Reinhart. The article conveys some information:

Combustion of solid and liquid fuels is the largest source of potentially toxic volatile organic compounds (VOCs), which can strongly affect health and the phys. and chem. properties of the atm. Among combustion processes, biomass burning is one of the largest at global scale. We used a Proton Transfer Reaction “”Time-of-Flight”” Mass Spectrometer (PTR-TOF-MS), which couples high sensitivity with high mass resolution, for real-time detection of multiple VOCs emitted by burned hay and straw in a barn located near our measuring station. We detected 132 different organic ions directly attributable to VOCs emitted from the fire. Methanol, acetaldehyde, acetone, Me vinyl ether (MVE), acetic acid and glycolaldehyde dominated the VOC mixture composition The time-course of the 25 most abundant VOCs, representing ∼85% of the whole mixture of VOCs, was associated with that of carbon monoxide (CO), carbon dioxide (CO2) and methane (CH4) emissions. The strong linear relationship between the concentrations of pyrogenic VOC and of a reference species (i.e. CO) allowed us to compile a list of emission ratios (ERs) and emission factors (EFs), but values of ER (and EF) were overestimated due to the limited mixing of the gases under the stable (non-turbulent) nocturnal conditions. In addition to the 25 most abundant VOCs, chem. formula and concentrations of the residual, less abundant VOCs in the emitted mixture were also estimated by PTR-TOF-MS. Furthermore, the evolution of the complex combustion process was described on the basis of the diverse types of pyrogenic gases recorded. The experimental part of the paper was very detailed, including the reaction process of 1-Butyl-1H-pyrazole(cas: 52096-24-9Application In Synthesis of 1-Butyl-1H-pyrazole)

1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Application In Synthesis of 1-Butyl-1H-pyrazole

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics