Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 5431-44-7, Name is 2,6-Pyridinedicarboxaldehyde. In a document, author is Ye, Pengqing, introducing its new discovery. COA of Formula: C7H5NO2.
Rare-Earth-Metal-Catalyzed Synthesis of Azaindolines and Naphthyridines via C-H Cyclization of Functionalized Pyridines
We report herein a rare-earth-metal-catalyzed insertion of a 2-pyridine C(sp(2))-H bond into an intramolecular unactivated vinyl bond. This reaction provides streamlined access to a range of azaindolines in moderate to excellent yields. The salient features of this reaction include simple and mild reaction conditions, 100% atom efficiency, and wide substrate scope. This methodology is also used to construct other nitrogen-containing compounds such as naphthyridine derivatives. A plausible mechanism for the formation of azaindolines involving initial C-H bond activation by the lanthanide complex followed by C=C insertion into a Ln-C bond to form an alkyl lanthanide species that subsequently undergoes cyclization is proposed.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 5431-44-7 help many people in the next few years. COA of Formula: C7H5NO2.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem