Related Products of 18704-37-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 18704-37-5, name is Quinoline-8-sulfonyl chloride, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: To a solution of 3-(1H-tetrazol-5-yl)aniline (1 eq.) in DCM dry (25 mL) at room temperature and under nitrogen atmosphere, pyridine (3 eq.) and the appropriate sulfonyl-chloride (1.2 eq.) were added. The mixture was reacted at room temperature for 2-12 h. The reaction was quenched with aqueous saturated solution of NH4Cl and acidified at pH 4 with aqueous 1N HCl. The aqueous phase was extracted with AcOEt, and the organic phase washed with brine, dried over Na2SO4 and concentrated. The crude was crystalized from MeOH or Et2O to give the desired product.
The chemical industry reduces the impact on the environment during synthesis Quinoline-8-sulfonyl chloride. I believe this compound will play a more active role in future production and life.