Application of 6715-84-0

The chemical industry reduces the impact on the environment during synthesis Methyl 4-Nitro-1H-pyrazole-1-acetate. I believe this compound will play a more active role in future production and life.

Related Products of 6715-84-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6715-84-0, name is Methyl 4-Nitro-1H-pyrazole-1-acetate, This compound has unique chemical properties. The synthetic route is as follows.

A clear, pale yellow solution of methyl 2-(4-nitro-1H-pyrazol-1-yl)acetate (0.250 g, 1.35 mmol) in EtOH (27.0 ml) was degassed with argon for 10 min. Then 10% Pd-C (0.072 g, 0.068 mmol) was added. The reaction was degassed with hydrogen from a balloon for several minutes and then the reaction was stirred vigorously under a hydrogen atmosphere. After 3 h, the reaction was stopped. The vessel was purged with argon/vacuum three times. Then Celite was added. After 10 min, the reaction was filtered through a plug of Celite, rinsing with EtOH, to give a clear, colorless filtrate. The filtrate was concentrated to give methyl 2-(4-amino-1H-pyrazol-1-yl)acetate (0.204 g, 97 % yield) as a clear, orange oil. The material was used in the next step without further purification. MS(ESI) m/z: 156.1 (M+H)+.

The chemical industry reduces the impact on the environment during synthesis Methyl 4-Nitro-1H-pyrazole-1-acetate. I believe this compound will play a more active role in future production and life.