Category: 139755-99-0

Electric Literature of 139755-99-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 139755-99-0, name is 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows.

Step 4: Synthesis of I -methyl-4-nitro-3 -propyl- 1 H-pyrazole-5-carboxylic acid:- Dissolve 1-methyl-3-propyl-1H-pyrazole-5-carboxylic acid (13.0 gm 7.7 m.ml) in 20 mlof conc.H2S04 and heated at 50 C. After that nitric mixture (9 ml) was added slowly over an 1 hour after the addition mixture was stirred at 50 C for 7 hours and then cooled to room temperature before being poured onto ice. Filteration of the precipitate gave the nitropyrazole as a white solid; Yield 88%. 1H NMR (400 MHz, CDC13) 6 4.10 (s, 3H) 2.50 (t, J=7.6Hz, 3H) 1.70 (m 2H) 1.02(t, J=7.6Hz, 3H) ppm ESI {M + Na] :236.07

The chemical industry reduces the impact on the environment during synthesis 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid. I believe this compound will play a more active role in future production and life.

A common compound: 139755-99-0, name is 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid, belongs to pyrazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below. 139755-99-0

Step 5 2-Methyl-4-nitro-5-propyl-2H-pyrazole-3-carboxylic acid: A solution of 2-methyl-5-propyl-2H-pyrazole-3-carboxylic acid (22 g, 131 mmol) in concentrated sulfuric acid (98%, 85 mL) was heated to 50 C. and treated with a mixture of fuming nitric acid (95%, 7.7 mL) and concentrated sulfuric acid (98%, 18 mL), while keeping the reaction temperature between 50 and 55 C. The reaction mixture was kept for 8 hours at 50 C., cooled to ambient temperature, and slowly added to cold water (600 mL, 4 C.), keeping the temperature below 25 C. The precipitate was collected by filtration, and dried below 80 C. to give the title compound as a white solid (25 g, 90%). 1H NMR (300 MHz, CDCl3) delta 4.25 (s, 3H), 2.92 (t, 2H, J=7.5 Hz), 1.77-1.70 (m, 2H), 1.03 (t, 3H, J=7.2 Hz); LC-MS: m/z=214 (M+H)+

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 139755-99-0, other downstream synthetic routes, hurry up and to see.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 139755-99-0, name is 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows., 139755-99-0

To a solution of I-04a (9.5 g, 56.54 mmol) was dissolved in conc. H2S04 (40 mL). Then conc. H2S04:H NO3 (3.6 mL:8 mL) was added into the reactionmixture slowly, and stirred at 50 00 overnight. The reaction mixture was poured into ice-water and filtered, the filtrate cake was collected and concentrated under vacuo to give I-05a (8 g, 71 .11% yield). ESI-MS (Mi-i):214 calc. for C9H11N304: 213.1

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