3-(1H-Pyrazol-3-yl)pyridine (cas: 45887-08-9) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.Category: pyrazoles-derivatives
Ligand Coordination Site-Directed Assembly of Copper(I) Iodide Complexes of ((Pyridyl)-1-pyrazolyl)pyridine was written by Li, Jun-Chi;Li, Hong-Xi;Li, Hai-Yan;Gong, Wei-Jie;Lang, Jian-Ping. And the article was included in Crystal Growth & Design in 2016.Category: pyrazoles-derivatives This article mentions the following:
((Pyridinyl)-1H-pyrazolyl)pyridine (pypzpy) ligands in which the pyrazolyl ring at 1 and 3 positions is substituted by two 2-, 3-, or 4-pyridyl groups were prepared Reaction of CuI with 2-(1-(pyridin-2-yl)-1H-pyrazolyl)pyridine (2,2′-pypzpy) in MeCN at room temperature or solvothermal reaction of the same components at 120° afforded a binuclear complex [{(2,2′-pypzpy)Cu}(μ-I)]2 (1). Treatment of CuI with 3-(1-(pyridin-2-yl)-1H-pyrazolyl)pyridine (3,2′-pypzpy) at room temperature or at 120° produced 1-dimensional (1D) polymer [{Cu3(μ3-I)3}(μ-3,2′-pypzpy)]n (2) and one two-dimensional (2D) polymer [{Cu2(μ-I)(μ3-I)}2(3,2′-pypzpy)2]n (3), resp. Similar reactions of CuI with 4-(1-(pyridin-2-yl)-1H-pyrazolyl)pyridine (4,2′-pypzpy) at room temperature or at 150° yielded one 1-dimensional polymeric complex [{Cu(μ3-I)}2(4,2′-pypzpy)2{Cu(μ-I)}2]n (4). [{Cu3(μ3-I)3}(μ-2,3′-pypzpy)]n (5), [(CuI)(μ-2,3′-pypzpy)]2 (6), [(Cu2I2)(3,3′-pypzpy)] (7), [(CuI)(4,3′-pypzpy)] (8), [{Cu(μ3-I)}2(μ-2,4′-pypzpy)2{Cu(μ-I)}2]n (9), [(CuI)(3,4′-pypzpy)] (10), and [(CuI)(μ-4,4′-pypzpy)]n (11) could be isolated by solution reactions or solvothermal reactions of CuI with 2-, 3-, 4-(1-(pyridin-3-yl)-1H-pyrazolyl)pyridine (2,3′-, 3,3′-, 4,3′-pypzpy), or 2-, 3-, 4-(1-(pyridin-4-yl)-1H-pyrazolyl)pyridine (2,4′-, 3,4′-, 4,4′-pypzpy). Compounds 1–11 were characterized by IR, elemental anal., powder x-ray diffraction, and single-crystal X-ray crystallog. Complex 1 contains a normal [Cu(μ-I)]2 dimeric structure. 2 And 5 consist of a unique displaced staircase chain [Cu2(μ3-I)2]n. Complex 3 has a 2-dimensional network formed by linking chairlike [Cu2(μ-I)(μ3-I)]2 units with two pairs of 3,2′-pypzpy bridges. Complexes 4 and 9 have a rare 1-dimensional triple chain, in which one internal 1-dimensional ladder-like chain [Cu2(μ3-I)2]n is connected with two zigzag chains [Cu(μ-I)]n via 4,2′-pypzpy or 2,4′-pypzpy ligands. 6 Consists of two [CuI] units interconnected by two 2,3′-pypzpy ligands. Compound 11 contains a 1-dimensional chain assembled by monomeric [CuI] units and 4,4′-pypzpy ligands. The luminescent properties of 1–11 in solid state were also studied at room temperature These results offer an interesting insight into how the coordination sites of the pypzpy ligands exert great impact on their coordination modes, the coordination spheres of the Cu(I) centers, the formation of the [CunIn] motifs and the topol. structures of the final complexes. In the experiment, the researchers used many compounds, for example, 3-(1H-Pyrazol-3-yl)pyridine (cas: 45887-08-9Category: pyrazoles-derivatives).
3-(1H-Pyrazol-3-yl)pyridine (cas: 45887-08-9) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.Category: pyrazoles-derivatives
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics